Expression of FGF23 and α-KLOTHO in Normal Human Kidney Development and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)

Expression of FGF23 and α-KLOTHO in Normal Human Kidney Development and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)

Congenital anomalies of the kidney and urinary tract (CAKUT) are a major cause of pediatric renal failure, but the molecular mechanisms driving these conditions are not yet fully understood. Fibroblast Growth Factor 23 (FGF23) and its co-receptor α-KLOTHO play crucial roles in regulating calcium and...

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Main Authors: Patricija Bajt, Anita Racetin, Nela Kelam, Nikola Pavlović, Petar Todorović, Marinela Jelinčić Korčulanin, Natalija Filipović, Ivana Kuzmić Prusac, Fila Raguž, Katarina Vukojević
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
FGF23
α-KLOTHO
CAKUT
congenital anomalies of the kidney and urinary tract
Online Access:https://www.mdpi.com/2218-273X/15/6/811
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