Protocol to identify the sex and CCR5 genotype of the human donor cells and tissues transplanted into humanized immune system mice

Summary: Humanized immune system (HIS) mouse models are commonly used for HIV studies; however, there is a need for sex-based data analysis. Here, we present a protocol to screen human donors for the CCR5delta32 (Δ32) polymorphism, which confers resistance to HIV infection, and identify the sex of t...

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Bibliographic Details
Main Authors: Saurav S. Rout, Kerry J. Lavender
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725000474
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