Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding
Background: Abnormal uterine bleeding (AUB) is one of the most common presenting health issues amongst females. It is defined as any bleeding that varies in frequency, duration, and volume of blood flow. Endometrial biopsy followed by histopathology constitutes an important mode of investigatio...
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ADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCES
2025-04-01
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| Series: | Journal of Medical Sciences and Health |
| Online Access: | https://jmsh.ac.in/articles/pattern-of-bleeding-with-histopathological-correlation-in-patients-presenting-with-abnormal-uterine-bleeding |
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| author | Ranjan Agrawal Gaurav Jaiswal Muhammad Ekram Mayank Agrawal |
| author_facet | Ranjan Agrawal Gaurav Jaiswal Muhammad Ekram Mayank Agrawal |
| author_sort | Ranjan Agrawal |
| collection | DOAJ |
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Background: Abnormal uterine bleeding (AUB) is one of the most common presenting health issues amongst females. It is defined as any bleeding that varies in frequency, duration, and volume of blood flow. Endometrial biopsy followed by histopathology constitutes an important mode of investigation in patients presenting with AUB. The aim of this study was to analyze the histopathological patterns of endometrium in females who present with AUB and to assess the patterns in age various groups. Methods: The study was conducted in a tertiary care hospital of Western Uttar Pradesh, during one year duration. Endometrial biopsies of patients presenting with AUB, in whom all causes of pregnancy were ruled out, have been included in the present study. Results: Out of the 130 cases studied, the majority of biopsies were in the age group of 41-50 years (55.4%). Most of the patients presented with complaints of menorrhagia (70%). The most common histological pattern observed were endometrium in proliferative (35.4%) followed by secretory phase (19.2%). Endometrial hyperplasia was another important histopathological finding observed. Only two cases of endometrial carcinoma were reported during the present study period. Conclusion: Although a regular cyclical pattern of menstruation is observed commonly noted, endometrial biopsy should be done in the peri- and post-menopausal age groups wherein the incidence of endometrial hyperplasia and endometrial carcinoma is more commonly observed.
Keywords: AUB, Endometrium, Polyp, Biopsy |
| format | Article |
| id | doaj-art-595084e11cd448948cc2036f201fb799 |
| institution | Kabale University |
| issn | 2394-9481 2394-949X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | ADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCES |
| record_format | Article |
| series | Journal of Medical Sciences and Health |
| spelling | doaj-art-595084e11cd448948cc2036f201fb7992025-08-20T03:45:30ZengADICHUNCHANAGIRI INSTITUTE OF MEDICAL SCIENCESJournal of Medical Sciences and Health2394-94812394-949X2025-04-011111710.46347/jmsh.v11.i1.24.230Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine BleedingRanjan AgrawalGaurav JaiswalMuhammad EkramMayank Agrawal Background: Abnormal uterine bleeding (AUB) is one of the most common presenting health issues amongst females. It is defined as any bleeding that varies in frequency, duration, and volume of blood flow. Endometrial biopsy followed by histopathology constitutes an important mode of investigation in patients presenting with AUB. The aim of this study was to analyze the histopathological patterns of endometrium in females who present with AUB and to assess the patterns in age various groups. Methods: The study was conducted in a tertiary care hospital of Western Uttar Pradesh, during one year duration. Endometrial biopsies of patients presenting with AUB, in whom all causes of pregnancy were ruled out, have been included in the present study. Results: Out of the 130 cases studied, the majority of biopsies were in the age group of 41-50 years (55.4%). Most of the patients presented with complaints of menorrhagia (70%). The most common histological pattern observed were endometrium in proliferative (35.4%) followed by secretory phase (19.2%). Endometrial hyperplasia was another important histopathological finding observed. Only two cases of endometrial carcinoma were reported during the present study period. Conclusion: Although a regular cyclical pattern of menstruation is observed commonly noted, endometrial biopsy should be done in the peri- and post-menopausal age groups wherein the incidence of endometrial hyperplasia and endometrial carcinoma is more commonly observed. Keywords: AUB, Endometrium, Polyp, Biopsyhttps://jmsh.ac.in/articles/pattern-of-bleeding-with-histopathological-correlation-in-patients-presenting-with-abnormal-uterine-bleeding |
| spellingShingle | Ranjan Agrawal Gaurav Jaiswal Muhammad Ekram Mayank Agrawal Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding Journal of Medical Sciences and Health |
| title | Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding |
| title_full | Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding |
| title_fullStr | Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding |
| title_full_unstemmed | Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding |
| title_short | Pattern of Bleeding with Histopathological Correlation in Patients Presenting with Abnormal Uterine Bleeding |
| title_sort | pattern of bleeding with histopathological correlation in patients presenting with abnormal uterine bleeding |
| url | https://jmsh.ac.in/articles/pattern-of-bleeding-with-histopathological-correlation-in-patients-presenting-with-abnormal-uterine-bleeding |
| work_keys_str_mv | AT ranjanagrawal patternofbleedingwithhistopathologicalcorrelationinpatientspresentingwithabnormaluterinebleeding AT gauravjaiswal patternofbleedingwithhistopathologicalcorrelationinpatientspresentingwithabnormaluterinebleeding AT muhammadekram patternofbleedingwithhistopathologicalcorrelationinpatientspresentingwithabnormaluterinebleeding AT mayankagrawal patternofbleedingwithhistopathologicalcorrelationinpatientspresentingwithabnormaluterinebleeding |