The silence within: a conserved intragenic silencing element governs HTLV-1 expression via host RUNX1 complex binding
A defining feature of Human T-cell leukaemia virus type 1 (HTLV-1) infection is the establishment of reversible latency that can persist for many years. This latency enables the expansion of infected CD4+ T cells, ultimately contributing to adult T-cell leukaemia (ATL) and inflammatory disease. Suga...
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| Main Authors: | Natasha Jansz, Damian F. J. Purcell |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | npj Viruses |
| Online Access: | https://doi.org/10.1038/s44298-025-00136-7 |
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