Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report
Ulfa Fetriani,1 Wahyu Hidayat2 1Oral Medicine Residency Program, Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, West Java, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, West Java, IndonesiaCorrespondence: Ulfa Fet...
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Dove Medical Press
2025-06-01
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| author | Fetriani U Hidayat W |
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| description | Ulfa Fetriani,1 Wahyu Hidayat2 1Oral Medicine Residency Program, Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, West Java, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, West Java, IndonesiaCorrespondence: Ulfa Fetriani, Oral Medicine Residency Program, Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Jalan Sekeloa Selatan I, Bandung, West Java, 40132, Indonesia, Tel +62 8971557962, Fax +62 22 7794121, Email ulfa23001@mail.unpad.ac.idBackground: Patients who receive chemotherapy or radiotherapy may experience oral complications such as oral mucositis, xerostomia, dental caries, periodontal disease, tissue fibrosis, opportunistic infections of the mucous membranes, neurosensory disorders, loss of taste, osteoradionecrosis, and trismus. This complication often causes high morbidity, oral frailty, and decreased quality of life. Oral mucositis is a common side effect of radiotherapy and often causes nutritional disorders and interruption in treatment.Purpose: This case report shows topical management in radiotherapy-treated geriatric patients with multiple oral lesions. It also shows the effectiveness of topical therapy for oral lesions in this case.Case Presentation: A 76-year-old male patient underwent radiotherapy for stage 4 nasal squamous cell carcinoma. After 22 radiotherapy sessions, the patient developed oral mucositis Grade 3 based on WHO criteria, characterized by painful ulcers, trismus, and dysphagia.Case Management: The patient was given topical drug therapy with a combination of 0.9% NaCl compress, 0.025% hyaluronic acid mouthwash, and petroleum jelly. Significant improvement was observed within five days, and resolution of oral mucositis occurred at the third visit.Conclusion: Management of oral lesions in geriatric patients receiving radiotherapy or chemotherapy is useful to prevent disruption of treatment and reduce the risk of oral frailty.Keywords: geriatric, oral frailty, oral lesion, oral mucositis, squamous cell carcinoma |
| format | Article |
| id | doaj-art-594ce04eb80c4304bc405186b9c46bc2 |
| institution | DOAJ |
| issn | 1179-142X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj-art-594ce04eb80c4304bc405186b9c46bc22025-08-20T03:24:00ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2025-06-01Volume 18Issue 1663669103509Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case ReportFetriani U0Hidayat W1oral medicineoral medicineUlfa Fetriani,1 Wahyu Hidayat2 1Oral Medicine Residency Program, Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, West Java, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Bandung, West Java, IndonesiaCorrespondence: Ulfa Fetriani, Oral Medicine Residency Program, Department of Oral Medicine, Faculty of Dentistry, Padjadjaran University, Jalan Sekeloa Selatan I, Bandung, West Java, 40132, Indonesia, Tel +62 8971557962, Fax +62 22 7794121, Email ulfa23001@mail.unpad.ac.idBackground: Patients who receive chemotherapy or radiotherapy may experience oral complications such as oral mucositis, xerostomia, dental caries, periodontal disease, tissue fibrosis, opportunistic infections of the mucous membranes, neurosensory disorders, loss of taste, osteoradionecrosis, and trismus. This complication often causes high morbidity, oral frailty, and decreased quality of life. Oral mucositis is a common side effect of radiotherapy and often causes nutritional disorders and interruption in treatment.Purpose: This case report shows topical management in radiotherapy-treated geriatric patients with multiple oral lesions. It also shows the effectiveness of topical therapy for oral lesions in this case.Case Presentation: A 76-year-old male patient underwent radiotherapy for stage 4 nasal squamous cell carcinoma. After 22 radiotherapy sessions, the patient developed oral mucositis Grade 3 based on WHO criteria, characterized by painful ulcers, trismus, and dysphagia.Case Management: The patient was given topical drug therapy with a combination of 0.9% NaCl compress, 0.025% hyaluronic acid mouthwash, and petroleum jelly. Significant improvement was observed within five days, and resolution of oral mucositis occurred at the third visit.Conclusion: Management of oral lesions in geriatric patients receiving radiotherapy or chemotherapy is useful to prevent disruption of treatment and reduce the risk of oral frailty.Keywords: geriatric, oral frailty, oral lesion, oral mucositis, squamous cell carcinomahttps://www.dovepress.com/radiotherapy-associated-oral-lesions-in-a-geriatric-patient-with-nasal-peer-reviewed-fulltext-article-IMCRJgeriatricoral frailtyoral lesionoral mucositissquamous cell carcinoma |
| spellingShingle | Fetriani U Hidayat W Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report International Medical Case Reports Journal geriatric oral frailty oral lesion oral mucositis squamous cell carcinoma |
| title | Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report |
| title_full | Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report |
| title_fullStr | Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report |
| title_full_unstemmed | Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report |
| title_short | Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report |
| title_sort | radiotherapy associated oral lesions in a geriatric patient with nasal squamous cell carcinoma a case report |
| topic | geriatric oral frailty oral lesion oral mucositis squamous cell carcinoma |
| url | https://www.dovepress.com/radiotherapy-associated-oral-lesions-in-a-geriatric-patient-with-nasal-peer-reviewed-fulltext-article-IMCRJ |
| work_keys_str_mv | AT fetrianiu radiotherapyassociatedorallesionsinageriatricpatientwithnasalsquamouscellcarcinomaacasereport AT hidayatw radiotherapyassociatedorallesionsinageriatricpatientwithnasalsquamouscellcarcinomaacasereport |