Neoadjuvant Multiagent Systemic Therapy Approach to Liver Transplantation for Perihilar Cholangiocarcinoma

Neoadjuvant Multiagent Systemic Therapy Approach to Liver Transplantation for Perihilar Cholangiocarcinoma

Background. Perihilar cholangiocarcinoma (phCCA) has excellent outcomes following liver transplantation (LT). Neoadjuvant radiation-based locoregional therapy is standard-of-care. Gemcitabine and cisplatin (gem/cis) combination systemic therapies have improved outcomes in advanced settings, but thei...

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Main Authors: Nadine Soliman, MD, Ashton A. Connor, MD, PhD, Ashish Saharia, MD, Sudha Kodali, MD, MSPH, Ahmed Elaileh, MD, Khush Patel, MD, MS, Samar Semaan, MD, Tamneet Basra, MD, David W. Victor, III, MD, Caroline J. Simon, MD, Yee Lee Cheah, MD, Mark J. Hobeika, MD, Constance M. Mobley, MD, PhD, Mukul Divatia, MD, Sadhna Dhingra, MD, Mary Schwartz, MD, Anaum Maqsood, MD, Kirk Heyne, MD, Maen Abdelrahim, MD, PhD, Milind Javle, MD, Jean-Nicolas Vauthey, MD, A. Osama Gaber, MD, R. Mark Ghobrial, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2025-03-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001760
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