Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
Abstract Background Angiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1–7), which activates the Mas receptor and elicits vasodilation, increased blood flow, reduced inflammation, and decreased...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-02-01
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| Series: | Journal of Biological Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13036-025-00482-3 |
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