Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series
There is growing evidence of left ventricular decompensation following the closure of the patent ductus arteriosus, which most often happens early in the post-surgical time and improves on its own a few months after. Here, we aim to present nine cases whose left ventricular ejection fraction deterio...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-05-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X251336987 |
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| author | Mohammad Reza Sabri Chehreh Mahdavi Hamid Bigdelian Ali Reza Ahmadi Mehdi Ghaderian Bahar Dehghan Davood Ramezani Nezhad |
| author_facet | Mohammad Reza Sabri Chehreh Mahdavi Hamid Bigdelian Ali Reza Ahmadi Mehdi Ghaderian Bahar Dehghan Davood Ramezani Nezhad |
| author_sort | Mohammad Reza Sabri |
| collection | DOAJ |
| description | There is growing evidence of left ventricular decompensation following the closure of the patent ductus arteriosus, which most often happens early in the post-surgical time and improves on its own a few months after. Here, we aim to present nine cases whose left ventricular ejection fraction deteriorated early or late after the procedure. There were nine patients diagnosed with patent ductus arteriosus by echocardiography. The patients presented with a murmur, easy fatigability, exercise intolerance, and poor weight gain. The age varied from 5 months to 41 years old. Patients developed left ventricular ejection fraction deterioration, starting from the day after the operation to 3 years after the closure. Pre-closure left ventricular ejection fraction ranged from 60% to 75% and post-closure from 33% to 59%. The range for shortening fraction (SF) was from 30% to 42% and 16% to 31%, respectively. The patent ductus arteriosus was moderate to large in all patients. One patient was finally diagnosed with dilated cardiomyopathy. Patients with patent ductus arteriosus show left ventricular ejection fraction deterioration up to years after closure, whether percutaneous or operative. Large patent ductus arteriosus is associated with more complications and reduced post-surgery cardiac function due to the amount of the shunt before closure. |
| format | Article |
| id | doaj-art-5921223c27894db9848a2f668f6bbef2 |
| institution | Kabale University |
| issn | 2050-313X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj-art-5921223c27894db9848a2f668f6bbef22025-08-20T03:49:27ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-05-011310.1177/2050313X251336987Transient left ventricular function deterioration after patent ductus arteriosus closure: A case seriesMohammad Reza Sabri0Chehreh Mahdavi1Hamid Bigdelian2Ali Reza Ahmadi3Mehdi Ghaderian4Bahar Dehghan5Davood Ramezani Nezhad6Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranCardiovascular Research Institute, Interventional Cardiology Research Center, Isfahan University of Medical Sciences, IranPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranThere is growing evidence of left ventricular decompensation following the closure of the patent ductus arteriosus, which most often happens early in the post-surgical time and improves on its own a few months after. Here, we aim to present nine cases whose left ventricular ejection fraction deteriorated early or late after the procedure. There were nine patients diagnosed with patent ductus arteriosus by echocardiography. The patients presented with a murmur, easy fatigability, exercise intolerance, and poor weight gain. The age varied from 5 months to 41 years old. Patients developed left ventricular ejection fraction deterioration, starting from the day after the operation to 3 years after the closure. Pre-closure left ventricular ejection fraction ranged from 60% to 75% and post-closure from 33% to 59%. The range for shortening fraction (SF) was from 30% to 42% and 16% to 31%, respectively. The patent ductus arteriosus was moderate to large in all patients. One patient was finally diagnosed with dilated cardiomyopathy. Patients with patent ductus arteriosus show left ventricular ejection fraction deterioration up to years after closure, whether percutaneous or operative. Large patent ductus arteriosus is associated with more complications and reduced post-surgery cardiac function due to the amount of the shunt before closure.https://doi.org/10.1177/2050313X251336987 |
| spellingShingle | Mohammad Reza Sabri Chehreh Mahdavi Hamid Bigdelian Ali Reza Ahmadi Mehdi Ghaderian Bahar Dehghan Davood Ramezani Nezhad Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series SAGE Open Medical Case Reports |
| title | Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series |
| title_full | Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series |
| title_fullStr | Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series |
| title_full_unstemmed | Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series |
| title_short | Transient left ventricular function deterioration after patent ductus arteriosus closure: A case series |
| title_sort | transient left ventricular function deterioration after patent ductus arteriosus closure a case series |
| url | https://doi.org/10.1177/2050313X251336987 |
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