Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors

Endovascular stent graft placement has become a major treatment for thoracic and abdominal aneurysms. While endovascular therapy is less invasive than open surgery, it involves the use of a contrast medium. Contrast media can cause renal impairment, a condition termed as contrast-induced nephropathy...

Full description

Saved in:
Bibliographic Details
Main Authors: Yohei Kawatani, Yoshitsugu Nakamura, Yoshihiko Mochida, Naoya Yamauchi, Yujiro Hayashi, Tetsuyoshi Taneichi, Yujiro Ito, Hirotsugu Kurobe, Yuji Suda, Takaki Hori
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Radiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/5950986
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849411844116054016
author Yohei Kawatani
Yoshitsugu Nakamura
Yoshihiko Mochida
Naoya Yamauchi
Yujiro Hayashi
Tetsuyoshi Taneichi
Yujiro Ito
Hirotsugu Kurobe
Yuji Suda
Takaki Hori
author_facet Yohei Kawatani
Yoshitsugu Nakamura
Yoshihiko Mochida
Naoya Yamauchi
Yujiro Hayashi
Tetsuyoshi Taneichi
Yujiro Ito
Hirotsugu Kurobe
Yuji Suda
Takaki Hori
author_sort Yohei Kawatani
collection DOAJ
description Endovascular stent graft placement has become a major treatment for thoracic and abdominal aneurysms. While endovascular therapy is less invasive than open surgery, it involves the use of a contrast medium. Contrast media can cause renal impairment, a condition termed as contrast-induced nephropathy (CIN). This study sought to evaluate the incidence and risk factors of CIN following endovascular stent graft placement for aortic aneurysm repair. The study included 167 consecutive patients who underwent endovascular stent graft placement in our hospital from October 2013 to June 2014. CIN was diagnosed using the European Society of Urogenital Radiology criteria. Patients with and without CIN were compared. Chi-squared tests, t-tests, and multivariate logistic regression analyses were performed. Thirteen patients (7.8%) developed CIN. Left ventricular dysfunction and intraoperative blood transfusion were significantly more frequent in the CIN group (P=0.017 and P=0.032, resp.). Multivariate analysis showed that left ventricular dysfunction had the strongest influence on CIN development (odds ratio 9.34, P=0.018, and 95% CI = 1.46–59.7). Patients with CIN also experienced longer ICU and hospital stays. Measures to improve renal perfusion flow should be considered for patients with left ventricular dysfunction who are undergoing endovascular stent graft placement.
format Article
id doaj-art-591f76b1aab64210a9fce7c0e025c74f
institution Kabale University
issn 2090-1941
2090-195X
language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Radiology Research and Practice
spelling doaj-art-591f76b1aab64210a9fce7c0e025c74f2025-08-20T03:34:40ZengWileyRadiology Research and Practice2090-19412090-195X2016-01-01201610.1155/2016/59509865950986Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk FactorsYohei Kawatani0Yoshitsugu Nakamura1Yoshihiko Mochida2Naoya Yamauchi3Yujiro Hayashi4Tetsuyoshi Taneichi5Yujiro Ito6Hirotsugu Kurobe7Yuji Suda8Takaki Hori9Department of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Clinical Engineer, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Clinical Engineer, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanDepartment of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, JapanEndovascular stent graft placement has become a major treatment for thoracic and abdominal aneurysms. While endovascular therapy is less invasive than open surgery, it involves the use of a contrast medium. Contrast media can cause renal impairment, a condition termed as contrast-induced nephropathy (CIN). This study sought to evaluate the incidence and risk factors of CIN following endovascular stent graft placement for aortic aneurysm repair. The study included 167 consecutive patients who underwent endovascular stent graft placement in our hospital from October 2013 to June 2014. CIN was diagnosed using the European Society of Urogenital Radiology criteria. Patients with and without CIN were compared. Chi-squared tests, t-tests, and multivariate logistic regression analyses were performed. Thirteen patients (7.8%) developed CIN. Left ventricular dysfunction and intraoperative blood transfusion were significantly more frequent in the CIN group (P=0.017 and P=0.032, resp.). Multivariate analysis showed that left ventricular dysfunction had the strongest influence on CIN development (odds ratio 9.34, P=0.018, and 95% CI = 1.46–59.7). Patients with CIN also experienced longer ICU and hospital stays. Measures to improve renal perfusion flow should be considered for patients with left ventricular dysfunction who are undergoing endovascular stent graft placement.http://dx.doi.org/10.1155/2016/5950986
spellingShingle Yohei Kawatani
Yoshitsugu Nakamura
Yoshihiko Mochida
Naoya Yamauchi
Yujiro Hayashi
Tetsuyoshi Taneichi
Yujiro Ito
Hirotsugu Kurobe
Yuji Suda
Takaki Hori
Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors
Radiology Research and Practice
title Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors
title_full Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors
title_fullStr Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors
title_full_unstemmed Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors
title_short Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors
title_sort contrast medium induced nephropathy after endovascular stent graft placement an examination of its prevalence and risk factors
url http://dx.doi.org/10.1155/2016/5950986
work_keys_str_mv AT yoheikawatani contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT yoshitsugunakamura contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT yoshihikomochida contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT naoyayamauchi contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT yujirohayashi contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT tetsuyoshitaneichi contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT yujiroito contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT hirotsugukurobe contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT yujisuda contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors
AT takakihori contrastmediuminducednephropathyafterendovascularstentgraftplacementanexaminationofitsprevalenceandriskfactors