Cognitive impairments in some cardiovascular and somatic diseases

The paper gives an update on the pathogenesis, clinical presentation, and pathomorphology of cognitive impairments (CIs) in different autoimmune, endocrine, and infectious diseases: systemic lupus erythematosus, Sjögren’s syndrome, Behchet’s disease, primary angiitis of the central nervous system, p...

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Main Author: N. V. Pizova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2015-06-01
Series:Неврология, нейропсихиатрия, психосоматика
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Online Access:https://nnp.ima-press.net/nnp/article/view/519
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author N. V. Pizova
author_facet N. V. Pizova
author_sort N. V. Pizova
collection DOAJ
description The paper gives an update on the pathogenesis, clinical presentation, and pathomorphology of cognitive impairments (CIs) in different autoimmune, endocrine, and infectious diseases: systemic lupus erythematosus, Sjögren’s syndrome, Behchet’s disease, primary angiitis of the central nervous system, polyarteritis nodosa, cryoglobulinemic vasculitis, hypothyroidism, herpetic lesion, and neurosyphilis. It is noted that treatment for CIs should be individual in terms of virulence factors. In vascular CIs, therapy should be aimed primarily at modifying risk factors and eliminating or reducing chronic brain ischemia. The prevention of progressive CI encompasses antihypertensive and antithrombotic therapies and surgical correction of atherosclerotic great artery stenosis. Control of hyperlipidemia, hyperglycemia and treatment of other somatic diseases are also of great importance. Such patients are usually given cetylcholinesterase inhibitors, acetylcholine precursors, antiglutamatergic agents, and metabolic and vascular drugs. By taking into account brain ischemia/ hypoxia in the above diseases, it is shown to be advisable to use antioxidants, cerebral active agents in particular, which have a complex neurometabolic effect.
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spelling doaj-art-591cd032e0ee4187af9f54895484a5212025-08-20T02:16:14ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422015-06-01729310010.14412/2074-2711-2015-2-93-100491Cognitive impairments in some cardiovascular and somatic diseasesN. V. Pizova0Department of Neurology and Medical Genetics with Course of Neurosurgery, Yaroslavl State Medical University, Ministry of Health of Russia, Yaroslavl, Russia 5, Revolutsionnaya St., Yaroslavl 150000The paper gives an update on the pathogenesis, clinical presentation, and pathomorphology of cognitive impairments (CIs) in different autoimmune, endocrine, and infectious diseases: systemic lupus erythematosus, Sjögren’s syndrome, Behchet’s disease, primary angiitis of the central nervous system, polyarteritis nodosa, cryoglobulinemic vasculitis, hypothyroidism, herpetic lesion, and neurosyphilis. It is noted that treatment for CIs should be individual in terms of virulence factors. In vascular CIs, therapy should be aimed primarily at modifying risk factors and eliminating or reducing chronic brain ischemia. The prevention of progressive CI encompasses antihypertensive and antithrombotic therapies and surgical correction of atherosclerotic great artery stenosis. Control of hyperlipidemia, hyperglycemia and treatment of other somatic diseases are also of great importance. Such patients are usually given cetylcholinesterase inhibitors, acetylcholine precursors, antiglutamatergic agents, and metabolic and vascular drugs. By taking into account brain ischemia/ hypoxia in the above diseases, it is shown to be advisable to use antioxidants, cerebral active agents in particular, which have a complex neurometabolic effect.https://nnp.ima-press.net/nnp/article/view/519cognitive impairmentsautoimmune, endocrine, and infectious diseasestreatment
spellingShingle N. V. Pizova
Cognitive impairments in some cardiovascular and somatic diseases
Неврология, нейропсихиатрия, психосоматика
cognitive impairments
autoimmune, endocrine, and infectious diseases
treatment
title Cognitive impairments in some cardiovascular and somatic diseases
title_full Cognitive impairments in some cardiovascular and somatic diseases
title_fullStr Cognitive impairments in some cardiovascular and somatic diseases
title_full_unstemmed Cognitive impairments in some cardiovascular and somatic diseases
title_short Cognitive impairments in some cardiovascular and somatic diseases
title_sort cognitive impairments in some cardiovascular and somatic diseases
topic cognitive impairments
autoimmune, endocrine, and infectious diseases
treatment
url https://nnp.ima-press.net/nnp/article/view/519
work_keys_str_mv AT nvpizova cognitiveimpairmentsinsomecardiovascularandsomaticdiseases