Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels

BackgroundThe treatment of sepsis relies on antibiotics following infection; however, the emergence of resistant bacteria necessitates the development of new therapeutic agents. Irisin has been shown to alleviate symptoms in septic mice, although its mechanism of action remains unclear. Our aim was...

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Bibliographic Details
Main Authors: Zeen Gong, Yunyan Ji, Haiyang Wu, Linli Xue, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Juan Wang, Yanjun Dong, Haidong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1618699/full
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