Regulatory role of lncRNA MSTRG.11540.1 on the novel-m1192-3p/CYP2C70 axis in modulating albendazole resistance in Haemonchus contortus

Regulatory role of lncRNA MSTRG.11540.1 on the novel-m1192-3p/CYP2C70 axis in modulating albendazole resistance in Haemonchus contortus

Abstract Background To investigate the role of long non-coding RNAs (lncRNAs) in the regulation of albendazole resistance in Haemonchus contortus (H. contortus) through competing endogenous RNA (ceRNA) mechanisms, a ceRNA network analysis was performed based on RNA-seq data from albendazole-sensitiv...

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Bibliographic Details
Main Authors: Xindi Chen, Tengyu Wang, Xu Yan, Ya Su, Wa Gao, Chunxia Liu, Huilin Kou, Yu Yu, Xianran Meng, Wenlong Wang, Wenrui Guo
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Veterinary Research
Subjects:
Haemonchus contortus
Albendazole
Drug resistance
LncRNA
CeRNA
RNAi
Online Access:https://doi.org/10.1186/s12917-025-04966-8
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