Brown adipose tissue: a potential therapeutic target for preventing cardiovascular disease in metabolic disorders

Brown adipose tissue: a potential therapeutic target for preventing cardiovascular disease in metabolic disorders

Abstract Background Obesity and Type 2 diabetes (T2D) remain significant health challenges contributing to cardiovascular complications. This study aimed to investigate brown adipose tissue (BAT) and connexin43 (Cx43) in obese T2D rats and evaluate the effects of antioxidant Cemtirestat. Cx43 plays...

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Main Authors:	Tamara Egan Beňová, Matúš Sýkora, Katarína Ondreják Andelová, Veronika Farkašová, Marek Lepáček, Marta Šoltésová Prnová, Pavel Babál, Dávid Janko, Natália Andelová, Miroslav Ferko, Barbara Szeiffová Bačová
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Series:	Diabetology & Metabolic Syndrome
Subjects:	ZDF rats Males Brown adipose tissue Connexin-43 Cemtirestat Uncoupling protein 1
Online Access:	https://doi.org/10.1186/s13098-025-01892-5
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