Astrocyte Kir4.1 expression level territorially controls excitatory transmission in the brain

Astrocyte Kir4.1 expression level territorially controls excitatory transmission in the brain

Summary: Intense brain activity elevates extracellular potassium, potentially leading to overexcitation and seizures. Astrocytes are crucial for restoring healthy potassium levels, and an emerging focus on their Kir4.1 channels has reopened the quest into the underlying mechanisms. We find that the...

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Bibliographic Details
Main Authors: Olga Tyurikova, Olga Kopach, Kaiyu Zheng, Daman Rathore, Neela Codadu, Sheng-Yi Wu, Yi Shen, Robert E. Campbell, Rob C. Wykes, Kirill Volynski, Leonid P. Savtchenko, Dmitri A. Rusakov
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725000701
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