Effect of HCH-contaminated diet on growth performance and serum characteristics in growing/finishing pigs

The experiment was conducted to study the effects of hexachlorocyclohexane (HCH) on growth performance, approach to the mechanism of effects by determining indexes of serum and hormone parameters. Seventy-two pigs, with equal number of barrows and gilts, the same genotype (Duroc × Landrace × Large W...

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Bibliographic Details
Main Authors: WANG Feng, XU Zi-rong, SUN Jian-hua
Format: Article
Language:English
Published: Zhejiang University Press 2006-05-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2006.03.0283
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Summary:The experiment was conducted to study the effects of hexachlorocyclohexane (HCH) on growth performance, approach to the mechanism of effects by determining indexes of serum and hormone parameters. Seventy-two pigs, with equal number of barrows and gilts, the same genotype (Duroc × Landrace × Large White), were randomly assigned to three groups receiving the same basal diet, adding to 0, 0.4, 0.8 mg·kg<sup>-1</sup> HCH respectively for 90 days. This experiment was conducted to investigate the effect of HCH on Growth performance and Serum characteristics of growing/finishing pigs. The results indicated that the average daily gain (ADG) and feed conversion rate (F/G) in growing/finishing pigs were not significantly affected by HCH. However, at groups exposed to 0.4 mg·kg<sup>-1</sup> and 0.8 mg·kg<sup>-1</sup> HCH in diet, Serum T3 was increased by 49.9% and 41.7% (P&lt;0.05), serum ALT activity was elevated by 11.2% (P&gt;0.05) and 26.9% (P&lt; 0.01), AKP activity was increased by 19.7% and 23.5% (P&lt;0.01), serum Superoxide dismutase (SOD) was decreased by 10.05% and 14.35% (P&lt;0.05) respectively. Serum Catalase (CAT) activity with 0.8 mg· kg<sup>-1</sup> HCH was decreased significantly by 14.21% (P&lt;0.05). These indicated that HCH led to the turbulence of hormone metabolism and the somatic lesion.
ISSN:1008-9209
2097-5155