Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products

<i>Perilla frutescens</i> (L.) Britt., a multifunctional herbaceous plant, is widely used in traditional medicine and cuisine due to its rich array of bioactive compounds. To date, many key phytochemicals in <i>P. frutescens</i> have been identified, including volatile terpen...

Full description

Saved in:
Bibliographic Details
Main Authors: Dandan Yi, Zhiyong Wang, Mu Peng
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/14/7/1252
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849738629511905280
author Dandan Yi
Zhiyong Wang
Mu Peng
author_facet Dandan Yi
Zhiyong Wang
Mu Peng
author_sort Dandan Yi
collection DOAJ
description <i>Perilla frutescens</i> (L.) Britt., a multifunctional herbaceous plant, is widely used in traditional medicine and cuisine due to its rich array of bioactive compounds. To date, many key phytochemicals in <i>P. frutescens</i> have been identified, including volatile terpenoids (perillaldehyde, limonene,), flavonoids (luteolin, apigenin), and phenolic acids (rosmarinic acid derivatives), which exhibit significant antioxidant, anti-inflammatory, antiviral, anticancer, antibacterial, and blood sugar-lowering effects. Studies have shown that volatile oils, flavonoids, and phenolic acids in <i>P. frutescens</i> exert their effects in various experimental models. In food and industrial applications, <i>P. frutescens</i> shows innovative potential in functional foods, natural preservatives, and novel food additives, effectively extending food shelf life and providing antimicrobial protection. Moreover, research on the biology and genetic improvement of <i>P. frutescens</i> has provided new approaches to enhance its yield and bioactive content. Finally, this paper also discusses the safety and standardization issues of the plant, providing theoretical support for its widespread application.
format Article
id doaj-art-59004f71afad4c258c8dbbc425f20b34
institution DOAJ
issn 2304-8158
language English
publishDate 2025-04-01
publisher MDPI AG
record_format Article
series Foods
spelling doaj-art-59004f71afad4c258c8dbbc425f20b342025-08-20T03:06:30ZengMDPI AGFoods2304-81582025-04-01147125210.3390/foods14071252Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health ProductsDandan Yi0Zhiyong Wang1Mu Peng2College of Biological and Food Engineering, Hubei Minzu University, Enshi 445000, ChinaCollege of Biological and Food Engineering, Hubei Minzu University, Enshi 445000, ChinaCollege of Biological and Food Engineering, Hubei Minzu University, Enshi 445000, China<i>Perilla frutescens</i> (L.) Britt., a multifunctional herbaceous plant, is widely used in traditional medicine and cuisine due to its rich array of bioactive compounds. To date, many key phytochemicals in <i>P. frutescens</i> have been identified, including volatile terpenoids (perillaldehyde, limonene,), flavonoids (luteolin, apigenin), and phenolic acids (rosmarinic acid derivatives), which exhibit significant antioxidant, anti-inflammatory, antiviral, anticancer, antibacterial, and blood sugar-lowering effects. Studies have shown that volatile oils, flavonoids, and phenolic acids in <i>P. frutescens</i> exert their effects in various experimental models. In food and industrial applications, <i>P. frutescens</i> shows innovative potential in functional foods, natural preservatives, and novel food additives, effectively extending food shelf life and providing antimicrobial protection. Moreover, research on the biology and genetic improvement of <i>P. frutescens</i> has provided new approaches to enhance its yield and bioactive content. Finally, this paper also discusses the safety and standardization issues of the plant, providing theoretical support for its widespread application.https://www.mdpi.com/2304-8158/14/7/1252<i>Perilla frutescens</i>chemical compositionfunctional activityfunctional foods
spellingShingle Dandan Yi
Zhiyong Wang
Mu Peng
Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
Foods
<i>Perilla frutescens</i>
chemical composition
functional activity
functional foods
title Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
title_full Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
title_fullStr Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
title_full_unstemmed Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
title_short Comprehensive Review of <i>Perilla frutescens</i>: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
title_sort comprehensive review of i perilla frutescens i chemical composition pharmacological mechanisms and industrial applications in food and health products
topic <i>Perilla frutescens</i>
chemical composition
functional activity
functional foods
url https://www.mdpi.com/2304-8158/14/7/1252
work_keys_str_mv AT dandanyi comprehensivereviewofiperillafrutescensichemicalcompositionpharmacologicalmechanismsandindustrialapplicationsinfoodandhealthproducts
AT zhiyongwang comprehensivereviewofiperillafrutescensichemicalcompositionpharmacologicalmechanismsandindustrialapplicationsinfoodandhealthproducts
AT mupeng comprehensivereviewofiperillafrutescensichemicalcompositionpharmacologicalmechanismsandindustrialapplicationsinfoodandhealthproducts