Duck plague virus US3 kinase phosphorylates and induces STING degradation to inhibit innate immune responses

Duck plague virus US3 kinase phosphorylates and induces STING degradation to inhibit innate immune responses

Duck plague virus (DPV) causes the highest mortality rate among aquatic birds; however, its antago nistic mechanism against antiviral innate immune responses remains elusive. In this study, we systematically screened and found that most DPV genes have inhibitory potential for duck cyclic guanosine m...

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Bibliographic Details
Main Authors: Bin Tian, Yanming Tian, Dongjie Cai, Huanhuan Cao, Liping Wu, Mingshu Wang, Qiao Yang, Ying Wu, Renyong Jia, Dekang Zhu, Mafeng Liu, Shun Chen, Xinxin Zhao, Shaqiu Zhang, Juan Huang, Di Sun, Xumin Ou, Zhen Wu, Anchun Cheng
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Poultry Science
Subjects:
Alpha herpesvirus
US3 kinase
STING
Phosphorylation
Immune evasion
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125005796
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