Bacterial Microorganisms in Definitive Neonatal Sepsis
Background The proper diagnosis and treatment of neonatal sepsis is done depends on the understanding of its causative organisms. Objective The present study aimed to investigate the types of microorganisms in definitive neonatal sepsis. Methods Neonatal sepsis is a serious infectious disease with h...
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Guilan University of Medical Sciences
2023-07-01
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| Series: | مجله دانشگاه علوم پزشکی گیلان |
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| Online Access: | http://journal.gums.ac.ir/article-1-2556-en.pdf |
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| author | Hassan Boskabadi Maryam Zakerihamidi Fatemeh Bagheri Ali Taghipour |
| author_facet | Hassan Boskabadi Maryam Zakerihamidi Fatemeh Bagheri Ali Taghipour |
| author_sort | Hassan Boskabadi |
| collection | DOAJ |
| description | Background The proper diagnosis and treatment of neonatal sepsis is done depends on the understanding of its causative organisms.
Objective The present study aimed to investigate the types of microorganisms in definitive neonatal sepsis.
Methods Neonatal sepsis is a serious infectious disease with high mortality. And its diagnosed by blood culture. It includes early (appearance of clinical symptoms from birth to the third-seventh day) and late (from the third day to the twenty-eighth day) types with specific and sometimes common clinical symptoms. This cross-sectional study was performed on 266 neonates hospitalized with definitive sepsis in Ghaem Hospital in Mashhad from 2010 to 2020 using available sampling method. Infants suspected of bacterial infection who had positive blood cultures were included in the study. Type of bacterial organism, time of sepsis, main causes of death and need for mechanical ventilation were evaluated.
Results Eighty eight neonates had early sepsis and 197 neonates had late sepsis. The bacterial organism of early sepsis was gram negative as 70.1% and in late sepsis was gram negative as 77.1%. The most common causes of early sepsis were Klebsiella pneumonia 21 cases (23.9%), Staphylococcus epidermis 16 cases (18.2%) and 10 cases (11.4%) E. coli . And the most common causes of late sepsis were K. pneumonia 35 cases (25.4%), Enterobacter aeroginosa 25(18.1%), S. epidermis 12(8.7%) and E. coli 11(8%).
Conclusion K. pneumonia, S. epidermis and E. coli were three most common organisms in early neonatal sepsis and K. pneumonia, S. epidermis and Enterobacter were the most common organisms in late neonatal sepsis. |
| format | Article |
| id | doaj-art-58f146476801485aaa2aab8b34f73484 |
| institution | OA Journals |
| issn | 2008-4048 2008-4056 |
| language | fas |
| publishDate | 2023-07-01 |
| publisher | Guilan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گیلان |
| spelling | doaj-art-58f146476801485aaa2aab8b34f734842025-08-20T02:25:34ZfasGuilan University of Medical Sciencesمجله دانشگاه علوم پزشکی گیلان2008-40482008-40562023-07-0132296105Bacterial Microorganisms in Definitive Neonatal SepsisHassan Boskabadi0Maryam Zakerihamidi1Fatemeh Bagheri2Ali Taghipour3 Department of Pediatrics, School of medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Midwifery, School of Medical Sciences, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran. Department of Nursing, School of Medical Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Department of Health and Epidemiology, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran. Background The proper diagnosis and treatment of neonatal sepsis is done depends on the understanding of its causative organisms. Objective The present study aimed to investigate the types of microorganisms in definitive neonatal sepsis. Methods Neonatal sepsis is a serious infectious disease with high mortality. And its diagnosed by blood culture. It includes early (appearance of clinical symptoms from birth to the third-seventh day) and late (from the third day to the twenty-eighth day) types with specific and sometimes common clinical symptoms. This cross-sectional study was performed on 266 neonates hospitalized with definitive sepsis in Ghaem Hospital in Mashhad from 2010 to 2020 using available sampling method. Infants suspected of bacterial infection who had positive blood cultures were included in the study. Type of bacterial organism, time of sepsis, main causes of death and need for mechanical ventilation were evaluated. Results Eighty eight neonates had early sepsis and 197 neonates had late sepsis. The bacterial organism of early sepsis was gram negative as 70.1% and in late sepsis was gram negative as 77.1%. The most common causes of early sepsis were Klebsiella pneumonia 21 cases (23.9%), Staphylococcus epidermis 16 cases (18.2%) and 10 cases (11.4%) E. coli . And the most common causes of late sepsis were K. pneumonia 35 cases (25.4%), Enterobacter aeroginosa 25(18.1%), S. epidermis 12(8.7%) and E. coli 11(8%). Conclusion K. pneumonia, S. epidermis and E. coli were three most common organisms in early neonatal sepsis and K. pneumonia, S. epidermis and Enterobacter were the most common organisms in late neonatal sepsis.http://journal.gums.ac.ir/article-1-2556-en.pdfmicroorganismearly neonatal sepsislate neonatal sepsisgram-negative microbesgram-positive microbes |
| spellingShingle | Hassan Boskabadi Maryam Zakerihamidi Fatemeh Bagheri Ali Taghipour Bacterial Microorganisms in Definitive Neonatal Sepsis مجله دانشگاه علوم پزشکی گیلان microorganism early neonatal sepsis late neonatal sepsis gram-negative microbes gram-positive microbes |
| title | Bacterial Microorganisms in Definitive Neonatal Sepsis |
| title_full | Bacterial Microorganisms in Definitive Neonatal Sepsis |
| title_fullStr | Bacterial Microorganisms in Definitive Neonatal Sepsis |
| title_full_unstemmed | Bacterial Microorganisms in Definitive Neonatal Sepsis |
| title_short | Bacterial Microorganisms in Definitive Neonatal Sepsis |
| title_sort | bacterial microorganisms in definitive neonatal sepsis |
| topic | microorganism early neonatal sepsis late neonatal sepsis gram-negative microbes gram-positive microbes |
| url | http://journal.gums.ac.ir/article-1-2556-en.pdf |
| work_keys_str_mv | AT hassanboskabadi bacterialmicroorganismsindefinitiveneonatalsepsis AT maryamzakerihamidi bacterialmicroorganismsindefinitiveneonatalsepsis AT fatemehbagheri bacterialmicroorganismsindefinitiveneonatalsepsis AT alitaghipour bacterialmicroorganismsindefinitiveneonatalsepsis |