The Landscape of MET Exon 14 Skipping Mutations in Patients With Lung Cancer Identified by Next-Generation Sequencing

The Landscape of MET Exon 14 Skipping Mutations in Patients With Lung Cancer Identified by Next-Generation Sequencing

Introduction: MET exon 14 (METex14) skipping mutations are observed in approximately 0.9% to 4% of patients with NSCLC. This study aimed to compare the detection rates of METex14 skipping in Chinese patients with lung cancer using DNA-based next-generation sequencing (NGS) with capture-based library...

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Main Authors: Jia Liao, MD, Song Wu, MD, Yi Min, MD, Yiran Li, MD, Yuanhang Nie, MD, Quwen Chen, MD, Zhiliang Mao, MD, Qinglan Zong, MS, Ning Gao, MS, Ding Zhang, PhD, Weiquan Liang, MD
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:JTO Clinical and Research Reports
Subjects:
Lung cancer
Second generation sequencing
METex14 skipping
Amplicon-based library construction
Capture-based library construction
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364325000426
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