Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs
The effectiveness of combined drugs, consisting of chondroitin and glucosamine (GA) in the treatment of osteoarthritis (OA) is discussed. Due to their high safety and pleiotropic effects, these drugs can be used in patients with OA (primarily with metabolic and inflammatory phenotypes) and comorbid...
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| Language: | Russian |
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IMA-PRESS LLC
2021-04-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1133 |
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| author | E. V. Zonova |
| author_facet | E. V. Zonova |
| author_sort | E. V. Zonova |
| collection | DOAJ |
| description | The effectiveness of combined drugs, consisting of chondroitin and glucosamine (GA) in the treatment of osteoarthritis (OA) is discussed. Due to their high safety and pleiotropic effects, these drugs can be used in patients with OA (primarily with metabolic and inflammatory phenotypes) and comorbid diseases. The effect of oral chondroitin and GA on the intestinal microbiota is described: regulation of the composition, metabolic and immunological activity of intestinal microbiota. The relationship between the regular administration of chondroitin and GA and decrease in overall mortality and mortality from cardiovascular diseases, as well as the decrease of malignancy development risk is marked. |
| format | Article |
| id | doaj-art-58e424e27a7544fcb8dae3caf3104e25 |
| institution | Kabale University |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2021-04-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-58e424e27a7544fcb8dae3caf3104e252025-08-20T03:59:54ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-04-0115212613110.14412/1996-7012-2021-2-126-1312354Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugsE. V. Zonova0Novosibirsk state medical universityThe effectiveness of combined drugs, consisting of chondroitin and glucosamine (GA) in the treatment of osteoarthritis (OA) is discussed. Due to their high safety and pleiotropic effects, these drugs can be used in patients with OA (primarily with metabolic and inflammatory phenotypes) and comorbid diseases. The effect of oral chondroitin and GA on the intestinal microbiota is described: regulation of the composition, metabolic and immunological activity of intestinal microbiota. The relationship between the regular administration of chondroitin and GA and decrease in overall mortality and mortality from cardiovascular diseases, as well as the decrease of malignancy development risk is marked.https://mrj.ima-press.net/mrj/article/view/1133osteoarthritistreatmentsymptomatic slow-acting drugs in osteoarthritis treatmentglucosaminechondroitin sulfate |
| spellingShingle | E. V. Zonova Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs Современная ревматология osteoarthritis treatment symptomatic slow-acting drugs in osteoarthritis treatment glucosamine chondroitin sulfate |
| title | Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs |
| title_full | Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs |
| title_fullStr | Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs |
| title_full_unstemmed | Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs |
| title_short | Advantages of osteoarthritis combined treatment with symptomatic slow-acting drugs |
| title_sort | advantages of osteoarthritis combined treatment with symptomatic slow acting drugs |
| topic | osteoarthritis treatment symptomatic slow-acting drugs in osteoarthritis treatment glucosamine chondroitin sulfate |
| url | https://mrj.ima-press.net/mrj/article/view/1133 |
| work_keys_str_mv | AT evzonova advantagesofosteoarthritiscombinedtreatmentwithsymptomaticslowactingdrugs |