Lipitension today — disaster tomorrow: focus on elderly comorbid patients

In elderly and senile patients, a combination of hypertension and atherogenic dyslipidemia is often encountered, which, both separately and in combination ("lipitension"), are associated with a high risk of cardiovascular events. In clinical practice, it is not just the age itself that is...

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Main Authors: A. S. Skotnikov, V. D. Zakiev, A. D. Gvozdeva, L. G. Bektemirova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2025-05-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/6340
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author A. S. Skotnikov
V. D. Zakiev
A. D. Gvozdeva
L. G. Bektemirova
author_facet A. S. Skotnikov
V. D. Zakiev
A. D. Gvozdeva
L. G. Bektemirova
author_sort A. S. Skotnikov
collection DOAJ
description In elderly and senile patients, a combination of hypertension and atherogenic dyslipidemia is often encountered, which, both separately and in combination ("lipitension"), are associated with a high risk of cardiovascular events. In clinical practice, it is not just the age itself that is important, but the presence of geriatric syndromes in patients. In particular, frailty is characterized by a high risk of adverse outcomes and death, as well as loss of autonomy. This article presents current data on the efficacy and safety of antihypertensive and lipidlowering therapy in elderly patients. It also discusses the thesis that fixed-dose combination of amlodipine, perindopril and atorvastatin can increase adherence to therapy and ensure a balance between the efficacy and safety of treatment in elderly comorbid patients with a number of geriatric syndromes. The treatment of such patients is traditionally associated with polypharmacy and uncontrolled use of medications.
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institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2025-05-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-58dea7a98df84fa1a8e0acb9b23cc05e2025-08-20T03:43:45Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202025-05-0130410.15829/1560-4071-2025-63404386Lipitension today — disaster tomorrow: focus on elderly comorbid patientsA. S. Skotnikov0V. D. Zakiev1A. D. Gvozdeva2L. G. Bektemirova3Sechenov First Moscow State Medical University; Russian State Social UniversityPirogov Russian National Research Medical University, Russian Gerontology Research and Clinical CenterBotkin Multidisciplinary Research and Clinical CenterMain Clinical Hospital of the Ministry of Internal AffairsIn elderly and senile patients, a combination of hypertension and atherogenic dyslipidemia is often encountered, which, both separately and in combination ("lipitension"), are associated with a high risk of cardiovascular events. In clinical practice, it is not just the age itself that is important, but the presence of geriatric syndromes in patients. In particular, frailty is characterized by a high risk of adverse outcomes and death, as well as loss of autonomy. This article presents current data on the efficacy and safety of antihypertensive and lipidlowering therapy in elderly patients. It also discusses the thesis that fixed-dose combination of amlodipine, perindopril and atorvastatin can increase adherence to therapy and ensure a balance between the efficacy and safety of treatment in elderly comorbid patients with a number of geriatric syndromes. The treatment of such patients is traditionally associated with polypharmacy and uncontrolled use of medications.https://russjcardiol.elpub.ru/jour/article/view/6340comorbiditylipitensionelderly and senile agefrailtypolypharmacymulti-purpose polypill.
spellingShingle A. S. Skotnikov
V. D. Zakiev
A. D. Gvozdeva
L. G. Bektemirova
Lipitension today — disaster tomorrow: focus on elderly comorbid patients
Российский кардиологический журнал
comorbidity
lipitension
elderly and senile age
frailty
polypharmacy
multi-purpose polypill.
title Lipitension today — disaster tomorrow: focus on elderly comorbid patients
title_full Lipitension today — disaster tomorrow: focus on elderly comorbid patients
title_fullStr Lipitension today — disaster tomorrow: focus on elderly comorbid patients
title_full_unstemmed Lipitension today — disaster tomorrow: focus on elderly comorbid patients
title_short Lipitension today — disaster tomorrow: focus on elderly comorbid patients
title_sort lipitension today disaster tomorrow focus on elderly comorbid patients
topic comorbidity
lipitension
elderly and senile age
frailty
polypharmacy
multi-purpose polypill.
url https://russjcardiol.elpub.ru/jour/article/view/6340
work_keys_str_mv AT asskotnikov lipitensiontodaydisastertomorrowfocusonelderlycomorbidpatients
AT vdzakiev lipitensiontodaydisastertomorrowfocusonelderlycomorbidpatients
AT adgvozdeva lipitensiontodaydisastertomorrowfocusonelderlycomorbidpatients
AT lgbektemirova lipitensiontodaydisastertomorrowfocusonelderlycomorbidpatients