Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine

Anna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED) is the most common eat...

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Main Authors: Guerdjikova AI, Mori N, Casuto LS, McElroy S
Format: Article
Language:English
Published: Dove Medical Press 2016-04-01
Series:Neuropsychiatric Disease and Treatment
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Online Access:https://www.dovepress.com/novel-pharmacologic-treatment-in-acute-binge-eating-disorder-ndash-rol-peer-reviewed-fulltext-article-NDT
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author Guerdjikova AI
Mori N
Casuto LS
McElroy S
author_facet Guerdjikova AI
Mori N
Casuto LS
McElroy S
author_sort Guerdjikova AI
collection DOAJ
description Anna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED) is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. Keywords: binging, overeating, Vyvanse, stimulant, approved medication
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series Neuropsychiatric Disease and Treatment
spelling doaj-art-58c70c759f4e412e8976c495beceb4022025-08-20T02:24:17ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-04-01Volume 12Issue 183384126477Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamineGuerdjikova AI0Mori NCasuto LSMcElroy S1Lindner Center of HOPEDepartment of Psychiatry and NeuroscienceAnna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED) is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. Keywords: binging, overeating, Vyvanse, stimulant, approved medicationhttps://www.dovepress.com/novel-pharmacologic-treatment-in-acute-binge-eating-disorder-ndash-rol-peer-reviewed-fulltext-article-NDTKey words: binge eatinglisdexamfetamine dimesylatestimulantsovereating
spellingShingle Guerdjikova AI
Mori N
Casuto LS
McElroy S
Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
Neuropsychiatric Disease and Treatment
Key words: binge eating
lisdexamfetamine dimesylate
stimulants
overeating
title Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_full Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_fullStr Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_full_unstemmed Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_short Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine
title_sort novel pharmacologic treatment in acute binge eating disorder amp ndash role of lisdexamfetamine
topic Key words: binge eating
lisdexamfetamine dimesylate
stimulants
overeating
url https://www.dovepress.com/novel-pharmacologic-treatment-in-acute-binge-eating-disorder-ndash-rol-peer-reviewed-fulltext-article-NDT
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AT casutols novelpharmacologictreatmentinacutebingeeatingdisorderampndashroleoflisdexamfetamine
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