A multiscale model for heterogeneous tumor spheroid in vitro
In this paper, a novel multiscale method is proposed for the study of heterogeneous tumor spheroid growth in vitro. The entire tumor spheroid is described by an ellipsoid-based model while nutrient and other environmental factors are treated as continua. The ellipsoid-based discrete component is cap...
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Main Authors: | Zhan Chen, Yuting Zou |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2018-03-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2018016 |
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