Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England

Objectives Our aims were to investigate discrepancies between depressed patients’ GlobalRating of Change (GRC) and scores on the Patient Health Questionnaire depression module (PHQ-9). Our objectives were to ascertain patients’ views on the source and meaning of mismatches and assess their clinical...

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Main Authors: Alice Malpass, Glyn Lewis, Jude Robinson, Christopher Dowrick, Naila Khan, Louise Fusco
Format: Article
Language:English
Published: BMJ Publishing Group 2017-05-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/7/4/e014519.full
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author Alice Malpass
Glyn Lewis
Jude Robinson
Christopher Dowrick
Naila Khan
Louise Fusco
author_facet Alice Malpass
Glyn Lewis
Jude Robinson
Christopher Dowrick
Naila Khan
Louise Fusco
author_sort Alice Malpass
collection DOAJ
description Objectives Our aims were to investigate discrepancies between depressed patients’ GlobalRating of Change (GRC) and scores on the Patient Health Questionnaire depression module (PHQ-9). Our objectives were to ascertain patients’ views on the source and meaning of mismatches and assess their clinical significance.Design Qualitative study nested within a cohort, in a programme investigating the indications for prescribing antidepressants that will lead to a clinical benefit.Setting Primary care practices in north-west England.Participants We invited 32 adults with a recent diagnosis of depression and evidence of mismatch between GRC and PHQ-9 Scores to participate. Of these, 29 completed our interviews; most were women, identified as white British, had high school education or higher, were employed or retired and had been depressed for a long time.Main measures We conducted semistructured interviews with a topic guide, focusing on experiences of depression; treatment experiences and expectations; effectiveness of the questionnaires; reasons for the mismatch; and social factors. Interviews were transcribed and subjected to interpretative phenomenological analysis.Results We identified four themes as explanations for mismatch between GRC and PHQ-9: perceptions that GRC provided a more accurate assessment of current mental state than PHQ-9; impact of recent negative or positive life events on either measure; personal understanding of depression as normally fluctuating, and tendency to underscore on PHQ-9 as a means of self-motivation; and lack of recall.Conclusions The combined used of the PHQ-9 and a more open question better captures the patient’s unique experiences of mental health. This approach ascertains the relevance of symptoms to the individual’s experience and influences treatment decisions.Study registration This study was an element of NIHR Programme Grant RP-PG 0610 10048.
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spelling doaj-art-58bf33130d2249838ad60631235b337c2025-02-01T15:10:14ZengBMJ Publishing GroupBMJ Open2044-60552017-05-017410.1136/bmjopen-2016-014519Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in EnglandAlice Malpass0Glyn Lewis1Jude Robinson2Christopher Dowrick3Naila Khan4Louise Fusco53 School of Social and Community Based Medicine, University of Bristol, Bristol, UKUniversity College London, London, UK2 School of Social and Political Sciences, University of Glasgow, Glasgow, UKSchool of Population, Community and Behavioural Sciences, University of Liverpool, Liverpool2 Department of Psychological Sciences, University of Liverpool, Liverpool, UK2 Department of Psychological Sciences, University of Liverpool, Liverpool, UKObjectives Our aims were to investigate discrepancies between depressed patients’ GlobalRating of Change (GRC) and scores on the Patient Health Questionnaire depression module (PHQ-9). Our objectives were to ascertain patients’ views on the source and meaning of mismatches and assess their clinical significance.Design Qualitative study nested within a cohort, in a programme investigating the indications for prescribing antidepressants that will lead to a clinical benefit.Setting Primary care practices in north-west England.Participants We invited 32 adults with a recent diagnosis of depression and evidence of mismatch between GRC and PHQ-9 Scores to participate. Of these, 29 completed our interviews; most were women, identified as white British, had high school education or higher, were employed or retired and had been depressed for a long time.Main measures We conducted semistructured interviews with a topic guide, focusing on experiences of depression; treatment experiences and expectations; effectiveness of the questionnaires; reasons for the mismatch; and social factors. Interviews were transcribed and subjected to interpretative phenomenological analysis.Results We identified four themes as explanations for mismatch between GRC and PHQ-9: perceptions that GRC provided a more accurate assessment of current mental state than PHQ-9; impact of recent negative or positive life events on either measure; personal understanding of depression as normally fluctuating, and tendency to underscore on PHQ-9 as a means of self-motivation; and lack of recall.Conclusions The combined used of the PHQ-9 and a more open question better captures the patient’s unique experiences of mental health. This approach ascertains the relevance of symptoms to the individual’s experience and influences treatment decisions.Study registration This study was an element of NIHR Programme Grant RP-PG 0610 10048.https://bmjopen.bmj.com/content/7/4/e014519.full
spellingShingle Alice Malpass
Glyn Lewis
Jude Robinson
Christopher Dowrick
Naila Khan
Louise Fusco
Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
BMJ Open
title Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
title_full Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
title_fullStr Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
title_full_unstemmed Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
title_short Why are there discrepancies between depressed patients’ Global Rating of Change and scores on the Patient Health Questionnaire depression module? A qualitative study of primary care in England
title_sort why are there discrepancies between depressed patients global rating of change and scores on the patient health questionnaire depression module a qualitative study of primary care in england
url https://bmjopen.bmj.com/content/7/4/e014519.full
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