Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis
Abstract Pulmonary lymphoepithelial carcinoma (PLELC) is distinct subtype of primary lung cancer, closely associated with Epstein-Barr virus (EBV) infection. Histopathological features sometimes mimic granulomatous inflammation. We present the case of a woman who was doubted with pulmonary and lymph...
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| Format: | Article |
| Language: | English |
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BMC
2025-04-01
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| Series: | BMC Pulmonary Medicine |
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| Online Access: | https://doi.org/10.1186/s12890-025-03633-w |
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| author | Senlin Zhan Changyin Feng Kaihua Pang Hongjuan Qin Peize Zhang |
| author_facet | Senlin Zhan Changyin Feng Kaihua Pang Hongjuan Qin Peize Zhang |
| author_sort | Senlin Zhan |
| collection | DOAJ |
| description | Abstract Pulmonary lymphoepithelial carcinoma (PLELC) is distinct subtype of primary lung cancer, closely associated with Epstein-Barr virus (EBV) infection. Histopathological features sometimes mimic granulomatous inflammation. We present the case of a woman who was doubted with pulmonary and lymph node tuberculosis based on a pathological demonstration of granulomatous inflammation. A final diagnosis of PLELC was made after lung biopsy and EBV tests. Given the complex and rarely seen of the disease, further studies are needed to investigate the clinical and pathological manifestations in patients with PLELC. Clinical trial number: Not applicable. |
| format | Article |
| id | doaj-art-58bbf71c318e4d91b3d165a06f6d7197 |
| institution | DOAJ |
| issn | 1471-2466 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj-art-58bbf71c318e4d91b3d165a06f6d71972025-08-20T03:10:09ZengBMCBMC Pulmonary Medicine1471-24662025-04-012511610.1186/s12890-025-03633-wCase report: pulmonary lymphoepithelial carcinoma mimicking tuberculosisSenlin Zhan0Changyin Feng1Kaihua Pang2Hongjuan Qin3Peize Zhang4Department of Pulmonary Medicine and Tuberculosis, The Third People’s Hospital of ShenzhenDepartment of pathology, The Third People’s Hospital of ShenzhenDepartment of Pulmonary Medicine and Tuberculosis, The Third People’s Hospital of ShenzhenDepartment of Pulmonary Medicine and Tuberculosis, The Third People’s Hospital of ShenzhenDepartment of Pulmonary Medicine and Tuberculosis, The Third People’s Hospital of ShenzhenAbstract Pulmonary lymphoepithelial carcinoma (PLELC) is distinct subtype of primary lung cancer, closely associated with Epstein-Barr virus (EBV) infection. Histopathological features sometimes mimic granulomatous inflammation. We present the case of a woman who was doubted with pulmonary and lymph node tuberculosis based on a pathological demonstration of granulomatous inflammation. A final diagnosis of PLELC was made after lung biopsy and EBV tests. Given the complex and rarely seen of the disease, further studies are needed to investigate the clinical and pathological manifestations in patients with PLELC. Clinical trial number: Not applicable.https://doi.org/10.1186/s12890-025-03633-wPulmonary lymphoepithelial carcinomaPLELCTuberculosisGranulomatous inflammationLung biopsyEBV |
| spellingShingle | Senlin Zhan Changyin Feng Kaihua Pang Hongjuan Qin Peize Zhang Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis BMC Pulmonary Medicine Pulmonary lymphoepithelial carcinoma PLELC Tuberculosis Granulomatous inflammation Lung biopsy EBV |
| title | Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis |
| title_full | Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis |
| title_fullStr | Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis |
| title_full_unstemmed | Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis |
| title_short | Case report: pulmonary lymphoepithelial carcinoma mimicking tuberculosis |
| title_sort | case report pulmonary lymphoepithelial carcinoma mimicking tuberculosis |
| topic | Pulmonary lymphoepithelial carcinoma PLELC Tuberculosis Granulomatous inflammation Lung biopsy EBV |
| url | https://doi.org/10.1186/s12890-025-03633-w |
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