Is there a role of calcitonin gene-related peptide in cortical spreading depression mechanisms?– argument con.

Abstract Cortical spreading depression (CSD) is a wave of neuronal and glial depolarization followed by suppressed neural activity, thought to underlie migraine aura. While Calcitonin Gene-Related Peptide (CGRP) is well established in migraine pathophysiology, its role in CSD remains uncertain. This...

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Bibliographic Details
Main Author: Agustin Melo-Carrillo
Format: Article
Language:English
Published: BMC 2025-04-01
Series:The Journal of Headache and Pain
Online Access:https://doi.org/10.1186/s10194-025-02012-4
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