Subclinical hypothyroidism: treat or watch?

Manifest hypothyroidism occurs in more than 5 % of the population, while prevalence of subclinical hypothyroidism is much higher and reaches 15 %. In the practice of an endocrinologist, in most cases, the diagnosis and treatment of manifest hypothyroidism does not raise questions, while subclinical...

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Main Authors: I. A. Tsanava, S. V. Bulgakova, A. V. Melikova
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2021-03-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/108
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author I. A. Tsanava
S. V. Bulgakova
A. V. Melikova
author_facet I. A. Tsanava
S. V. Bulgakova
A. V. Melikova
author_sort I. A. Tsanava
collection DOAJ
description Manifest hypothyroidism occurs in more than 5 % of the population, while prevalence of subclinical hypothyroidism is much higher and reaches 15 %. In the practice of an endocrinologist, in most cases, the diagnosis and treatment of manifest hypothyroidism does not raise questions, while subclinical changes in thyroid hormones quite often generate a lot of discussions. The generally accepted reference range for TSH up to 4.50 μIU / ml is in conflict with data showing that more than 95 % of healthy people with euthyroidism have serum TSH levels up to 2.5 μIU / ml. At the same time, a lot of data has been accumulated on the effect of even slightly altered levels of thyroid hormones and TSH on various tissues, organs and systems of the body, especially on the cardiovascular, nervous and reproductive systems. This review analyzes the results of studies aimed at studying the relationship of subclinical hypothyroidism with cardiovascular and metabolic disorders, cognitive disorders, pathology of pregnant women.
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institution Kabale University
issn 2226-762X
2782-1579
language Russian
publishDate 2021-03-01
publisher Private institution educational organization of higher education "Medical University "ReaViz"
record_format Article
series Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
spelling doaj-art-58af705f37ca4e3ebac5ff935f91b71a2025-08-20T03:59:13ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792021-03-01069810810.20340/vmi-rvz.2020.6.12107Subclinical hypothyroidism: treat or watch?I. A. Tsanava0S. V. Bulgakova1A. V. Melikova2Medical University “Reaviz”Samara State Medical UniversityClinic of Five BlagosManifest hypothyroidism occurs in more than 5 % of the population, while prevalence of subclinical hypothyroidism is much higher and reaches 15 %. In the practice of an endocrinologist, in most cases, the diagnosis and treatment of manifest hypothyroidism does not raise questions, while subclinical changes in thyroid hormones quite often generate a lot of discussions. The generally accepted reference range for TSH up to 4.50 μIU / ml is in conflict with data showing that more than 95 % of healthy people with euthyroidism have serum TSH levels up to 2.5 μIU / ml. At the same time, a lot of data has been accumulated on the effect of even slightly altered levels of thyroid hormones and TSH on various tissues, organs and systems of the body, especially on the cardiovascular, nervous and reproductive systems. This review analyzes the results of studies aimed at studying the relationship of subclinical hypothyroidism with cardiovascular and metabolic disorders, cognitive disorders, pathology of pregnant women.https://vestnik.reaviz.ru/jour/article/view/108hypothyroidismsubclinical hypothyroidismthyroid hormonesthyroid-stimulating hormonelevothyroxine
spellingShingle I. A. Tsanava
S. V. Bulgakova
A. V. Melikova
Subclinical hypothyroidism: treat or watch?
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
hypothyroidism
subclinical hypothyroidism
thyroid hormones
thyroid-stimulating hormone
levothyroxine
title Subclinical hypothyroidism: treat or watch?
title_full Subclinical hypothyroidism: treat or watch?
title_fullStr Subclinical hypothyroidism: treat or watch?
title_full_unstemmed Subclinical hypothyroidism: treat or watch?
title_short Subclinical hypothyroidism: treat or watch?
title_sort subclinical hypothyroidism treat or watch
topic hypothyroidism
subclinical hypothyroidism
thyroid hormones
thyroid-stimulating hormone
levothyroxine
url https://vestnik.reaviz.ru/jour/article/view/108
work_keys_str_mv AT iatsanava subclinicalhypothyroidismtreatorwatch
AT svbulgakova subclinicalhypothyroidismtreatorwatch
AT avmelikova subclinicalhypothyroidismtreatorwatch