Pantothenic acid ameliorates hepatic fibrosis by targeting IGFBP6 to regulate the TGF-β/SMADs pathway

Pantothenic acid ameliorates hepatic fibrosis by targeting IGFBP6 to regulate the TGF-β/SMADs pathway

Abstract Hepatic fibrosis progression involves complex multicellular crosstalk, highlighting the critical need to identify key therapeutic targets. In this study, we identify insulin-like growth factor binding protein 6 (IGFBP6) as a marker specifically enriched in hepatic stellate cells (HSCs) and...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhengxin Jin, Zhengsen Jin, Zeyu Liu, Yongcheng Yin, Yuchen Zhang, Ying Zhang, Jianning Kang, Yuepeng Fang, Wei Jiang, Bin Ning
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08527-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items