A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma

Background: Three-dimensional (3D)-reconstruction from paraffin embedded sections has been considered laborious and time-consuming. However, the high-resolution images of large object areas and different fields of view obtained by 3D-reconstruction make one wonder whether it can add a new insight in...

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Main Authors: Maristela L. Onozato, Veronica E. Klepeis, Yukako Yagi, Mari Mino-Kenudson
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2011-0030
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author Maristela L. Onozato
Veronica E. Klepeis
Yukako Yagi
Mari Mino-Kenudson
author_facet Maristela L. Onozato
Veronica E. Klepeis
Yukako Yagi
Mari Mino-Kenudson
author_sort Maristela L. Onozato
collection DOAJ
description Background: Three-dimensional (3D)-reconstruction from paraffin embedded sections has been considered laborious and time-consuming. However, the high-resolution images of large object areas and different fields of view obtained by 3D-reconstruction make one wonder whether it can add a new insight into lung adenocarcinoma, the most frequent histology type of lung cancer characterized by its morphological heterogeneity.
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institution Kabale University
issn 2210-7177
2210-7185
language English
publishDate 2012-01-01
publisher Wiley
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series Analytical Cellular Pathology
spelling doaj-art-58a38068a30b44d896d596cc19ed223b2025-02-03T05:53:17ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-01352798410.3233/ACP-2011-0030A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung AdenocarcinomaMaristela L. Onozato0Veronica E. Klepeis1Yukako Yagi2Mari Mino-Kenudson3Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USADepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USADepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USADepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USABackground: Three-dimensional (3D)-reconstruction from paraffin embedded sections has been considered laborious and time-consuming. However, the high-resolution images of large object areas and different fields of view obtained by 3D-reconstruction make one wonder whether it can add a new insight into lung adenocarcinoma, the most frequent histology type of lung cancer characterized by its morphological heterogeneity.http://dx.doi.org/10.3233/ACP-2011-0030
spellingShingle Maristela L. Onozato
Veronica E. Klepeis
Yukako Yagi
Mari Mino-Kenudson
A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
Analytical Cellular Pathology
title A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
title_full A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
title_fullStr A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
title_full_unstemmed A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
title_short A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
title_sort role of three dimensional 3d reconstruction in the classification of lung adenocarcinoma
url http://dx.doi.org/10.3233/ACP-2011-0030
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