Involvement of Toll -like receptor 9 signaling in neutrophil extracellular traps-induced epithelial-to-mesenchymal transition in myositis-associated interstitial lung disease

Involvement of Toll -like receptor 9 signaling in neutrophil extracellular traps-induced epithelial-to-mesenchymal transition in myositis-associated interstitial lung disease

Objective The study aims to elucidate whether neutrophil extracellular traps (NETs) promote epithelial-mesenchymal transition (EMT) in alveolar epithelial cells via Toll-like receptor 9 (TLR9) signaling,thereby contributing to the development of idiopathic inflammatory myopathy-associated interstiti...

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Bibliographic Details
Main Authors: Feng Yingyue, Zhuo Cui, Su Qiyan, Cui Xi, Guo Jin, Zhu Jiarui, Zhang Sigong
Format: Article
Language:zho
Published: Lanzhou University Press 2024-12-01
Series:生物医学转化
Subjects:
neutrophil extracellular traps
inflammatory myopathy
interstitial lung disease
epithelial-mesenchymal transition
toll-like receptor 9
Online Access:http://swyxzh.ijournals.cn/swyxzh/article/html/20240411?st=article_issue
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