Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non‐small cell lung cancer patients
Abstract Background Topoisomerase 2‐alpha (TOP2A) is an enzyme that controls topologic changes in DNA during transcription and replication. ERCC1 is an enzyme that takes part in DNA repair processes. The purpose of this study was to assess the predictive role of particular single nucleotide polymorp...
Saved in:
| Main Authors: | Anna Grenda, Justyna Błach, Michał Szczyrek, Paweł Krawczyk, Marcin Nicoś, Barbara Kuźnar Kamińska, Monika Jakimiec, Grażyna Balicka, Izabela Chmielewska, Halina Batura‐Gabryel, Marek Sawicki, Janusz Milanowski |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.2743 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
ERCC1 as a Marker of Ovarian Cancer Resistance to Platinum Drugs
by: T. A. Bogush, et al.
Published: (2020-05-01) -
Trichothiodystrophy due to ERCC2 Variants: Uncommon Contributor to Progressive Hypomyelinating Leukodystrophy
by: Ali Reza Tavasoli, et al.
Published: (2025-02-01) -
<i>ERCC1</i> and <i>ERCC2</i> Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer
by: Andrés Barba, et al.
Published: (2024-08-01) -
The Quantitative Indices of ERCC1 Expression in Serous Ovarian Cancer Tissue and the Efficacy of First-Line Platinum-Based Chemotherapy
by: T. A. Bogush, et al.
Published: (2020-05-01) -
ERCC1/NGFR affects prognosis in basal-like breast cancer
by: Yuxi Lei, et al.
Published: (2025-07-01)