Ascorbic acid alleviates reproductive toxicity of di-(2-ethyl hexyl) phthalate in female Wistar rats

Ascorbic acid alleviates reproductive toxicity of di-(2-ethyl hexyl) phthalate in female Wistar rats

Objective: To investigate the potential of ascorbic acid in mitigating reproductive toxicity induced by di-(2-ethyl hexyl) phthalate (DEHP) in female Wistar rats, focusing on oxidative stress, hormone levels, and gonadotropin receptors expression. Methods: Forty female Wistar rats [30 days old, weig...

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Main Authors: Kalaivani Manokaran, Ravi Sankar Bhaskaran, Jayesh Mudgal, Prabu Paramasivam, Sachin Shetty, Deepak Nayak, Sunitha Carnelio, Vennila Jaganathan, Dharani Abirama Sundari Shanmugam, Karkala Sreedhara Ranganath Pai
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Asian Pacific Journal of Reproduction
Subjects:
di-(2-ethylhexyl) phthalate
ascorbic acid
oxidative stress
apoptosis
ovarian morphology
Online Access:https://journals.lww.com/10.4103/apjr.apjr_68_24
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