Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)

Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component condensation β-dicarbonyl compounds, aldehydes and ure...

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Main Authors: Mohammad R. Mohammadizadeh, Neda Firoozi
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/751282
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author Mohammad R. Mohammadizadeh
Neda Firoozi
author_facet Mohammad R. Mohammadizadeh
Neda Firoozi
author_sort Mohammad R. Mohammadizadeh
collection DOAJ
description Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component condensation β-dicarbonyl compounds, aldehydes and urea (thio).
format Article
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institution Kabale University
issn 0973-4945
2090-9810
language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-5867442b3bf6409e9d1457cf65a5a6532025-02-03T01:32:47ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-018S1S266S27010.1155/2011/751282Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)Mohammad R. Mohammadizadeh0Neda Firoozi1Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, IranDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, IranTrifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component condensation β-dicarbonyl compounds, aldehydes and urea (thio).http://dx.doi.org/10.1155/2011/751282
spellingShingle Mohammad R. Mohammadizadeh
Neda Firoozi
Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
E-Journal of Chemistry
title Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
title_full Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
title_fullStr Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
title_full_unstemmed Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
title_short Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
title_sort trifluoroacetic acid as an effective catalyst for biginelli reaction one pot three component synthesis of 3 4 dihydropyrimidin 2 1h ones and thiones
url http://dx.doi.org/10.1155/2011/751282
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AT nedafiroozi trifluoroaceticacidasaneffectivecatalystforbiginellireactiononepotthreecomponentsynthesisof34dihydropyrimidin21honesandthiones