Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs
Multiple myeloma is a neoplastic plasma cell disorder. It is characterized by collections of abnormal plasma cells accumulating in the bone marrow, where they interfere with the production of normal blood cells. It usually presents as a multisystemic involvement, whose symptoms and signs vary greatl...
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Wiley
2015-01-01
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Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2015/452305 |
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author | Murat Köse Ersida Buraniqi Timur Selçuk Akpinar Seyit Mehmet Kayacan Tufan Tükek |
author_facet | Murat Köse Ersida Buraniqi Timur Selçuk Akpinar Seyit Mehmet Kayacan Tufan Tükek |
author_sort | Murat Köse |
collection | DOAJ |
description | Multiple myeloma is a neoplastic plasma cell disorder. It is characterized by collections of abnormal plasma cells accumulating in the bone marrow, where they interfere with the production of normal blood cells. It usually presents as a multisystemic involvement, whose symptoms and signs vary greatly. Some patients have slowly progressive disease while others have aggressive clinical behavior by extramedullary involvement. In addition to renal failure, anemia, hypercalcemia, lytic bone lesions, and immunodeficiency, it also affects multiple organ system, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, lymph nodes, and bone. To raise awareness of the variable presentations of this disease, we report a 53-year-old male patient, with multiple myeloma in his first remission who relapsed with extramedullary plasmacytomas (EMPs) involving multiple organs, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, and lymph nodes. |
format | Article |
id | doaj-art-585fd5eeef3241ae9824ed2548a0e977 |
institution | Kabale University |
issn | 2090-6560 2090-6579 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Hematology |
spelling | doaj-art-585fd5eeef3241ae9824ed2548a0e9772025-02-03T05:45:38ZengWileyCase Reports in Hematology2090-65602090-65792015-01-01201510.1155/2015/452305452305Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple OrgansMurat Köse0Ersida Buraniqi1Timur Selçuk Akpinar2Seyit Mehmet Kayacan3Tufan Tükek4Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, TurkeyDepartment of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, TurkeyDepartment of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, TurkeyDepartment of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, TurkeyDepartment of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, TurkeyMultiple myeloma is a neoplastic plasma cell disorder. It is characterized by collections of abnormal plasma cells accumulating in the bone marrow, where they interfere with the production of normal blood cells. It usually presents as a multisystemic involvement, whose symptoms and signs vary greatly. Some patients have slowly progressive disease while others have aggressive clinical behavior by extramedullary involvement. In addition to renal failure, anemia, hypercalcemia, lytic bone lesions, and immunodeficiency, it also affects multiple organ system, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, lymph nodes, and bone. To raise awareness of the variable presentations of this disease, we report a 53-year-old male patient, with multiple myeloma in his first remission who relapsed with extramedullary plasmacytomas (EMPs) involving multiple organs, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, and lymph nodes.http://dx.doi.org/10.1155/2015/452305 |
spellingShingle | Murat Köse Ersida Buraniqi Timur Selçuk Akpinar Seyit Mehmet Kayacan Tufan Tükek Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs Case Reports in Hematology |
title | Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs |
title_full | Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs |
title_fullStr | Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs |
title_full_unstemmed | Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs |
title_short | Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs |
title_sort | relapse of multiple myeloma presenting as extramedullary plasmacytomas in multiple organs |
url | http://dx.doi.org/10.1155/2015/452305 |
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