Single-cell RNA sequencing reveals a new mechanism of endothelial cell heterogeneity and healing in diabetic foot ulcers

Single-cell RNA sequencing reveals a new mechanism of endothelial cell heterogeneity and healing in diabetic foot ulcers

Abstract Diabetic foot ulcers (DFU) are a common and severe complication among diabetic patients, posing a significant burden on patients’ quality of life and healthcare systems due to their high incidence, amputation rates, and mortality. This study utilized single-cell RNA sequencing technology to...

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Bibliographic Details
Main Authors: Songyun Zhao, Hua Yu, Zihao Li, Wanying Chen, Kaibo Liu, Hao Dai, Gaoyi Wang, Zibing Zhang, Jiaheng Xie, Yucang He, Liqun Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Biology Direct
Subjects:
Diabetic foot ulcers
Single-cell RNA sequencing
Endothelial cells
SH3BGRL3
Wound healing
Angiogenesis
Online Access:https://doi.org/10.1186/s13062-025-00628-9
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