Correlation Analysis of the Entorhinal Cortex-Hippocampus Nerve Fiber Changes and Memory Dysfunction in P301L-Tau Mouse Model and Molecular Mechanism

Correlation Analysis of the Entorhinal Cortex-Hippocampus Nerve Fiber Changes and Memory Dysfunction in P301L-Tau Mouse Model and Molecular Mechanism

ObjectiveTo observe the correlation between the changes of entorhinal cortex-hippocampus nerve fibers and learning and memory function in the P301L-Tau mouse model of Alzheimer's disease (AD) and related molecular mechanism, so as to provide the evidence for Tau-targeted treatment in AD patient...

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Bibliographic Details
Main Authors: CHEN Xiaocheng, LIANG Shengxiang, LIN Bingbing, LIU Weilin, HUANG Jia
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2023-04-01
Series:康复学报
Subjects:
Alzheimer's disease
phosphorylated Tau protein
diffusion tensor imaging
entorhinal cortex-hippocampus
learning and memory
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2023.02007
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