Examination of influenza specific T cell responses after influenza virus challenge in individuals vaccinated with MVA-NP+M1 vaccine.

Examination of influenza specific T cell responses after influenza virus challenge in individuals vaccinated with MVA-NP+M1 vaccine.

Current influenza vaccines stimulate neutralising antibody to the haemagglutinin antigen but as there is antigenic drift in HA it is difficult to prepare a vaccine in advance against an emergent strain. A potential strategy is to induce CD8(+) and CD4(+) T cells that recognize epitopes within intern...

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Bibliographic Details
Main Authors: Timothy J Powell, Yanchun Peng, Tamara K Berthoud, Marie-Eve Blais, Patrick J Lillie, Adrian V S Hill, Sarah L Rowland-Jones, Andrew J McMichael, Sarah C Gilbert, Tao Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0062778&type=printable
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