Cell Marker Accordion: interpretable single-cell and spatial omics annotation in health and disease

Cell Marker Accordion: interpretable single-cell and spatial omics annotation in health and disease

Abstract Single-cell technologies offer a unique opportunity to explore cellular heterogeneity in health and disease. However, reliable identification of cell types and states represents a bottleneck. Available databases and analysis tools employ dissimilar markers, leading to inconsistent annotatio...

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Main Authors: Emma Busarello, Giulia Biancon, Ilaria Cimignolo, Fabio Lauria, Zuhairia Ibnat, Christian Ramirez, Gabriele Tomè, Marianna Ciuffreda, Giorgia Bucciarelli, Alessandro Pilli, Stefano Maria Marino, Vittorio Bontempi, Federica Ress, Kristin R. Aass, Jennifer VanOudenhove, Luca Tiberi, Maria Caterina Mione, Therese Standal, Paolo Macchi, Gabriella Viero, Stephanie Halene, Toma Tebaldi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60900-4
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