Synthesis and Characterization of new Mannich Bases for Pyrazole containing Benimidazole Ring
This research includes synthesis of new derivatives of benzimidazole , the compound (A1*) prepared by reaction of o-phenylene diamine with carbon disulfide in alcoholic potassium hydroxide. Then the compound (A1*) was reaction with ethyl chloroacetate and potassium hydroxide to give ester (A2*). Th...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tikrit University
2023-01-01
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| Series: | Tikrit Journal of Pure Science |
| Subjects: | |
| Online Access: | https://tjpsj.org/index.php/tjps/article/view/592 |
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| Summary: | This research includes synthesis of new derivatives of benzimidazole , the compound (A1*) prepared by reaction of o-phenylene diamine with carbon disulfide in alcoholic potassium hydroxide. Then the compound (A1*) was reaction with ethyl chloroacetate and potassium hydroxide to give ester (A2*). Then preparation of hydrazide (A3*) by the reaction of (A2*) with hydrazine hydrate (80%). Then we used the hydrazide (A3*) to prepare pyrazole (A4), then preparation of mannich basses by reaction of compound (A4) with different primary aromatic amines and formaldehyde
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| ISSN: | 1813-1662 2415-1726 |