Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds
The increasing prevalence of toxic compounds in food, agriculture, and the environment presents a critical challenge to public health and ecological sustainability. Carbon nanodots (CNDs), with their excellent photoluminescence, biocompatibility, and ease of functionalization, have emerged as highly...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/15/10/725 |
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| author | Duyen H. H. Nguyen Arjun Muthu Tamer Elsakhawy Mohamed H. Sheta Neama Abdalla Hassan El-Ramady József Prokisch |
| author_facet | Duyen H. H. Nguyen Arjun Muthu Tamer Elsakhawy Mohamed H. Sheta Neama Abdalla Hassan El-Ramady József Prokisch |
| author_sort | Duyen H. H. Nguyen |
| collection | DOAJ |
| description | The increasing prevalence of toxic compounds in food, agriculture, and the environment presents a critical challenge to public health and ecological sustainability. Carbon nanodots (CNDs), with their excellent photoluminescence, biocompatibility, and ease of functionalization, have emerged as highly promising materials for developing advanced sensors that target hazardous substances. This review provides a comprehensive overview of the synthesis, functionalization, and sensing mechanisms of CND-based sensors, highlighting their versatile application in detecting toxic compounds such as heavy metals, pesticides, mycotoxins, and emerging contaminants. The article outlines recent advancements in fluorescence, electrochemical, and colorimetric detection strategies and presents key case studies that illustrate the successful application of CNDs in real-world monitoring scenarios. Furthermore, it addresses the challenges associated with reproducibility, scalability, selectivity, and sensor stability and explores future directions for integrating CNDs with smart and sustainable technologies. This review emphasizes the transformative potential of CNDs in achieving rapid, cost-effective, and environmentally friendly toxin detection solutions across multiple domains. |
| format | Article |
| id | doaj-art-582c727c75864585b808ebe5a2ea14ca |
| institution | DOAJ |
| issn | 2079-4991 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-582c727c75864585b808ebe5a2ea14ca2025-08-20T03:14:29ZengMDPI AGNanomaterials2079-49912025-05-01151072510.3390/nano15100725Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic CompoundsDuyen H. H. Nguyen0Arjun Muthu1Tamer Elsakhawy2Mohamed H. Sheta3Neama Abdalla4Hassan El-Ramady5József Prokisch6Institute of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Biotechnology and Nature Conservation, University of Debrecen, 138 Böszörményi Street, 4032 Debrecen, HungaryDoctoral School of Nutrition and Food Science, University of Debrecen, 4032 Debrecen, HungaryAgricultural Microbiology Research Department, Soils, Water and Environment Research Institute (SWERI), Agricultural Research Center (ARC), Giza 12619, EgyptSoils and Water Department, Faculty of Agriculture, Al-Azhar University, Cairo 11884, EgyptPlant Biotechnology Department, Biotechnology Research Institute, National Research Centre, 33 El Buhouth St., Dokki, Giza 12622, EgyptSoil and Water Department, Faculty of Agriculture, Kafrelsheikh University, Kafr El-Sheikh 33516, EgyptInstitute of Animal Science, Faculty of Agricultural and Food Sciences and Environmental Management, Biotechnology and Nature Conservation, University of Debrecen, 138 Böszörményi Street, 4032 Debrecen, HungaryThe increasing prevalence of toxic compounds in food, agriculture, and the environment presents a critical challenge to public health and ecological sustainability. Carbon nanodots (CNDs), with their excellent photoluminescence, biocompatibility, and ease of functionalization, have emerged as highly promising materials for developing advanced sensors that target hazardous substances. This review provides a comprehensive overview of the synthesis, functionalization, and sensing mechanisms of CND-based sensors, highlighting their versatile application in detecting toxic compounds such as heavy metals, pesticides, mycotoxins, and emerging contaminants. The article outlines recent advancements in fluorescence, electrochemical, and colorimetric detection strategies and presents key case studies that illustrate the successful application of CNDs in real-world monitoring scenarios. Furthermore, it addresses the challenges associated with reproducibility, scalability, selectivity, and sensor stability and explores future directions for integrating CNDs with smart and sustainable technologies. This review emphasizes the transformative potential of CNDs in achieving rapid, cost-effective, and environmentally friendly toxin detection solutions across multiple domains.https://www.mdpi.com/2079-4991/15/10/725rapid detectioncarbon dotsprobesheavy metalcontaminantsultrasensitive sensor devices |
| spellingShingle | Duyen H. H. Nguyen Arjun Muthu Tamer Elsakhawy Mohamed H. Sheta Neama Abdalla Hassan El-Ramady József Prokisch Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds Nanomaterials rapid detection carbon dots probes heavy metal contaminants ultrasensitive sensor devices |
| title | Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds |
| title_full | Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds |
| title_fullStr | Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds |
| title_full_unstemmed | Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds |
| title_short | Carbon Nanodots-Based Sensors: A Promising Tool for Detecting and Monitoring Toxic Compounds |
| title_sort | carbon nanodots based sensors a promising tool for detecting and monitoring toxic compounds |
| topic | rapid detection carbon dots probes heavy metal contaminants ultrasensitive sensor devices |
| url | https://www.mdpi.com/2079-4991/15/10/725 |
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