A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis

Abstract Background Staphylococcus lugdunensis is a coagulase-negative Staphylococcus species, which are weak pathogenic bacteria generally. However, the acute and severe pathogenicity of Staphylococcus lugdunensis infective endocarditis may be due to the rapid growth of large vegetation and consequ...

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Main Authors: Kazuhiro Yamazaki, Kenji Minakata, Kazuhisa Sakamoto, Jiro Sakai, Yujiro Ide, Masahide Kawatou, Hideo Kanemitsu, Tadashi Ikeda, Kenji Minatoya, Ryuzo Sakata
Format: Article
Language:English
Published: Japan Surgical Society 2020-11-01
Series:Surgical Case Reports
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Online Access:http://link.springer.com/article/10.1186/s40792-020-01062-x
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author Kazuhiro Yamazaki
Kenji Minakata
Kazuhisa Sakamoto
Jiro Sakai
Yujiro Ide
Masahide Kawatou
Hideo Kanemitsu
Tadashi Ikeda
Kenji Minatoya
Ryuzo Sakata
author_facet Kazuhiro Yamazaki
Kenji Minakata
Kazuhisa Sakamoto
Jiro Sakai
Yujiro Ide
Masahide Kawatou
Hideo Kanemitsu
Tadashi Ikeda
Kenji Minatoya
Ryuzo Sakata
author_sort Kazuhiro Yamazaki
collection DOAJ
description Abstract Background Staphylococcus lugdunensis is a coagulase-negative Staphylococcus species, which are weak pathogenic bacteria generally. However, the acute and severe pathogenicity of Staphylococcus lugdunensis infective endocarditis may be due to the rapid growth of large vegetation and consequent valve destruction. Case presentation The patient was an 81-year-old male who visited our hospital with chief complaints of low back pain and high fever. Four years before this visit, he had undergone aortic valve replacement for aortic regurgitation. He was found to be hypotensive. Although there is no heart murmur on auscultation and echocardiography revealed negative findings with aortic valve, a blood test showed increases in the white blood cell count and C-reactive protein concentration. On the next day, Gram-positive cocci were detected in a blood culture and echocardiography detected a large vegetation on the prosthetic valve with increased flow velocity. Therefore, he underwent redo aortic valve replacement emergently. Staphylococcus lugdunensis was identified in blood samples and vegetation culture. Consequently, the patient was treated with antibiotics for 5 weeks after the operation and discharged home. Conclusions We experienced rapidly progressive prosthetic valve endocarditis caused by Staphylococcus lugdunensis. Hence, Staphylococcus lugdunensis infective endocarditis requires aggressive treatment, and the pathogenicity of this coagulase-negative Staphylococcus with high drug susceptibility should not be underestimated.
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spelling doaj-art-581c9f48201246e1b15a9abb0fce76e22025-08-20T03:33:21ZengJapan Surgical SocietySurgical Case Reports2198-77932020-11-01611510.1186/s40792-020-01062-xA case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensisKazuhiro Yamazaki0Kenji Minakata1Kazuhisa Sakamoto2Jiro Sakai3Yujiro Ide4Masahide Kawatou5Hideo Kanemitsu6Tadashi Ikeda7Kenji Minatoya8Ryuzo Sakata9Department of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto UniversityAbstract Background Staphylococcus lugdunensis is a coagulase-negative Staphylococcus species, which are weak pathogenic bacteria generally. However, the acute and severe pathogenicity of Staphylococcus lugdunensis infective endocarditis may be due to the rapid growth of large vegetation and consequent valve destruction. Case presentation The patient was an 81-year-old male who visited our hospital with chief complaints of low back pain and high fever. Four years before this visit, he had undergone aortic valve replacement for aortic regurgitation. He was found to be hypotensive. Although there is no heart murmur on auscultation and echocardiography revealed negative findings with aortic valve, a blood test showed increases in the white blood cell count and C-reactive protein concentration. On the next day, Gram-positive cocci were detected in a blood culture and echocardiography detected a large vegetation on the prosthetic valve with increased flow velocity. Therefore, he underwent redo aortic valve replacement emergently. Staphylococcus lugdunensis was identified in blood samples and vegetation culture. Consequently, the patient was treated with antibiotics for 5 weeks after the operation and discharged home. Conclusions We experienced rapidly progressive prosthetic valve endocarditis caused by Staphylococcus lugdunensis. Hence, Staphylococcus lugdunensis infective endocarditis requires aggressive treatment, and the pathogenicity of this coagulase-negative Staphylococcus with high drug susceptibility should not be underestimated.http://link.springer.com/article/10.1186/s40792-020-01062-xStaphylococcus lugdunensisProsthetic valve endocarditisAortic valve replacement
spellingShingle Kazuhiro Yamazaki
Kenji Minakata
Kazuhisa Sakamoto
Jiro Sakai
Yujiro Ide
Masahide Kawatou
Hideo Kanemitsu
Tadashi Ikeda
Kenji Minatoya
Ryuzo Sakata
A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis
Surgical Case Reports
Staphylococcus lugdunensis
Prosthetic valve endocarditis
Aortic valve replacement
title A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis
title_full A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis
title_fullStr A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis
title_full_unstemmed A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis
title_short A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis
title_sort case of aggressive aortic prosthetic valve endocarditis aggressive caused by staphylococcus lugdunensis
topic Staphylococcus lugdunensis
Prosthetic valve endocarditis
Aortic valve replacement
url http://link.springer.com/article/10.1186/s40792-020-01062-x
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