Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review

Emphysematous pyelonephritis (EPN) is a rare but severe necrotizing infection often associated with diabetes, ureteral obstruction, and gas production in the renal parenchyma and perinephric area. This report describes a 54-year-old man with type 2 diabetes who presented with right lumbar pain and w...

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Main Authors: Pan Gao, Han Yang, Zhi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1512449/full
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author Pan Gao
Han Yang
Han Yang
Zhi Zhang
author_facet Pan Gao
Han Yang
Han Yang
Zhi Zhang
author_sort Pan Gao
collection DOAJ
description Emphysematous pyelonephritis (EPN) is a rare but severe necrotizing infection often associated with diabetes, ureteral obstruction, and gas production in the renal parenchyma and perinephric area. This report describes a 54-year-old man with type 2 diabetes who presented with right lumbar pain and was diagnosed with EPN complicated by right ureteral calculi and perinephric gas accumulation. Despite initial improvement with fluid resuscitation, antibiotics, and drainage, inadequate blood glucose control led to a worsening of the infection, eventually involving the psoas major muscle and iliac vessels. This progression resulted in the formation of an iliac aneurysm, which required endovascular surgery. The patient’s recovery was supported by proper blood glucose management and targeted antibiotic therapy. This case highlights the importance of early recognition, appropriate management, and strict glycemic control in preventing severe complications of EPN.
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publisher Frontiers Media S.A.
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series Frontiers in Medicine
spelling doaj-art-5800dcf3e52d494a8f336ee544b83aed2025-01-13T15:59:13ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.15124491512449Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and reviewPan Gao0Han Yang1Han Yang2Zhi Zhang3Department of Urology, Second People's Hospital of Yichang, Second People's Hospital of China Three Gorges University, Yichang, ChinaDepartment of Urology, Second People's Hospital of Yichang, Second People's Hospital of China Three Gorges University, Yichang, ChinaDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Urology, Second People's Hospital of Yichang, Second People's Hospital of China Three Gorges University, Yichang, ChinaEmphysematous pyelonephritis (EPN) is a rare but severe necrotizing infection often associated with diabetes, ureteral obstruction, and gas production in the renal parenchyma and perinephric area. This report describes a 54-year-old man with type 2 diabetes who presented with right lumbar pain and was diagnosed with EPN complicated by right ureteral calculi and perinephric gas accumulation. Despite initial improvement with fluid resuscitation, antibiotics, and drainage, inadequate blood glucose control led to a worsening of the infection, eventually involving the psoas major muscle and iliac vessels. This progression resulted in the formation of an iliac aneurysm, which required endovascular surgery. The patient’s recovery was supported by proper blood glucose management and targeted antibiotic therapy. This case highlights the importance of early recognition, appropriate management, and strict glycemic control in preventing severe complications of EPN.https://www.frontiersin.org/articles/10.3389/fmed.2024.1512449/fullemphysematous pyelonephritisdiabetesureteral calculianeurysmiliac aneurysm
spellingShingle Pan Gao
Han Yang
Han Yang
Zhi Zhang
Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review
Frontiers in Medicine
emphysematous pyelonephritis
diabetes
ureteral calculi
aneurysm
iliac aneurysm
title Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review
title_full Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review
title_fullStr Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review
title_full_unstemmed Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review
title_short Emphysematous pyelonephritis with rare and severe iliac vascular complications: a case report and review
title_sort emphysematous pyelonephritis with rare and severe iliac vascular complications a case report and review
topic emphysematous pyelonephritis
diabetes
ureteral calculi
aneurysm
iliac aneurysm
url https://www.frontiersin.org/articles/10.3389/fmed.2024.1512449/full
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AT hanyang emphysematouspyelonephritiswithrareandsevereiliacvascularcomplicationsacasereportandreview
AT zhizhang emphysematouspyelonephritiswithrareandsevereiliacvascularcomplicationsacasereportandreview