Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens

To evaluate the effects of Bacillus subtilis ZY1 supplementation, production performance, egg quality, serum parameters, and intestinal health in laying hens were investigated. A total of 240 healthy 59-week-old Hy-Line Brown laying hens were randomly assigned to four groups: a control group (Con) f...

Full description

Saved in:
Bibliographic Details
Main Authors: Rongrong Dong, Hao Liu, Huan Zhang, Fengyang Wu, Haidong Xiu, Shiwei Chen, Xinxiang Yin, Xiaohui Zhou
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Poultry Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125003591
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850219397426184192
author Rongrong Dong
Hao Liu
Huan Zhang
Fengyang Wu
Haidong Xiu
Shiwei Chen
Xinxiang Yin
Xiaohui Zhou
author_facet Rongrong Dong
Hao Liu
Huan Zhang
Fengyang Wu
Haidong Xiu
Shiwei Chen
Xinxiang Yin
Xiaohui Zhou
author_sort Rongrong Dong
collection DOAJ
description To evaluate the effects of Bacillus subtilis ZY1 supplementation, production performance, egg quality, serum parameters, and intestinal health in laying hens were investigated. A total of 240 healthy 59-week-old Hy-Line Brown laying hens were randomly assigned to four groups: a control group (Con) fed a basal diet and three treatment groups supplemented with Bacillus subtilis ZY1 at levels of 0.05 % (LG), 0.1 % (MG), and 0.2 % (HG). The duration of trial lasted eleven weeks, including a one-week pre-feeding phase. The results indicated that dietary supplementation with ZY1 increased the egg laying rate in the LG and HG groups (P < 0.05) as well as improved the qualified egg rate in the LG and MG groups (P < 0.05). Moreover, the LG group also demonstrated superior egg quality and enhanced antioxidant capacity and immune function by decreasing the level of MDA (42.47 %) and improving the content of T-AOC, GSH-Px, CAT, SOD, IgM and IgG (34.31 %, 23.92 %, 37.68 %, 31.64 %, 14.01 %, and 17.84 %, respectively) in serum samples (P < 0.05). The changes in biochemical parameters such as AST, LDH, TG (12.40 %, 13.79 %, and 32.13 % decreased, respectively) and Ca (41.35 % increased) were particularly pronounced in LG groups (P < 0.05), indicating that ZY1 supplementation enhanced metabolic capacity of laying hens (P < 0.05). Furthermore, laying hens in the treatment groups exhibited significantly increased villus height (VH) and an elevated villus height-to-crypt depth ratio (VH/CD) within their duodenal tissues (P < 0.05). These findings suggest that dietary supplementation with ZY1 effectively improves production performance, egg quality, serum parameters, and intestinal health in laying hens; notably, a dosage of 0.05 % ZY1 was identified as the optimal level for these improvements. This study provides valuable insights into optimizing the application of Bacillus subtilis ZY1 in laying hen management practices.
format Article
id doaj-art-57fefed5394d46f89909f97df9cae985
institution OA Journals
issn 0032-5791
language English
publishDate 2025-07-01
publisher Elsevier
record_format Article
series Poultry Science
spelling doaj-art-57fefed5394d46f89909f97df9cae9852025-08-20T02:07:23ZengElsevierPoultry Science0032-57912025-07-01104710512010.1016/j.psj.2025.105120Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hensRongrong Dong0Hao Liu1Huan Zhang2Fengyang Wu3Haidong Xiu4Shiwei Chen5Xinxiang Yin6Xiaohui Zhou7School of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050000, PR ChinaDepartment of Asset and Laboratory Management, Hebei University of Science and Technology, Shijiazhuang 050000, PR ChinaSchool of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050000, PR ChinaCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071000, PR ChinaSchool of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050000, PR ChinaHengshui River Animal Husbandry Co. Ltd., Hengshui, 053311, PR ChinaHebei Keweixian Biotechnology Co. Ltd., Hengshui, 053300, PR ChinaSchool of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050000, PR China; Corresponding author.To evaluate the effects of Bacillus subtilis ZY1 supplementation, production performance, egg quality, serum parameters, and intestinal health in laying hens were investigated. A total of 240 healthy 59-week-old Hy-Line Brown laying hens were randomly assigned to four groups: a control group (Con) fed a basal diet and three treatment groups supplemented with Bacillus subtilis ZY1 at levels of 0.05 % (LG), 0.1 % (MG), and 0.2 % (HG). The duration of trial lasted eleven weeks, including a one-week pre-feeding phase. The results indicated that dietary supplementation with ZY1 increased the egg laying rate in the LG and HG groups (P < 0.05) as well as improved the qualified egg rate in the LG and MG groups (P < 0.05). Moreover, the LG group also demonstrated superior egg quality and enhanced antioxidant capacity and immune function by decreasing the level of MDA (42.47 %) and improving the content of T-AOC, GSH-Px, CAT, SOD, IgM and IgG (34.31 %, 23.92 %, 37.68 %, 31.64 %, 14.01 %, and 17.84 %, respectively) in serum samples (P < 0.05). The changes in biochemical parameters such as AST, LDH, TG (12.40 %, 13.79 %, and 32.13 % decreased, respectively) and Ca (41.35 % increased) were particularly pronounced in LG groups (P < 0.05), indicating that ZY1 supplementation enhanced metabolic capacity of laying hens (P < 0.05). Furthermore, laying hens in the treatment groups exhibited significantly increased villus height (VH) and an elevated villus height-to-crypt depth ratio (VH/CD) within their duodenal tissues (P < 0.05). These findings suggest that dietary supplementation with ZY1 effectively improves production performance, egg quality, serum parameters, and intestinal health in laying hens; notably, a dosage of 0.05 % ZY1 was identified as the optimal level for these improvements. This study provides valuable insights into optimizing the application of Bacillus subtilis ZY1 in laying hen management practices.http://www.sciencedirect.com/science/article/pii/S0032579125003591ZY1Laying hensEgg qualitySerum parameterIntestinal morphology
spellingShingle Rongrong Dong
Hao Liu
Huan Zhang
Fengyang Wu
Haidong Xiu
Shiwei Chen
Xinxiang Yin
Xiaohui Zhou
Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens
Poultry Science
ZY1
Laying hens
Egg quality
Serum parameter
Intestinal morphology
title Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens
title_full Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens
title_fullStr Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens
title_full_unstemmed Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens
title_short Effects of Bacillus subtilis ZY1 on production performance, egg quality, serum parameters and intestinal health in laying hens
title_sort effects of bacillus subtilis zy1 on production performance egg quality serum parameters and intestinal health in laying hens
topic ZY1
Laying hens
Egg quality
Serum parameter
Intestinal morphology
url http://www.sciencedirect.com/science/article/pii/S0032579125003591
work_keys_str_mv AT rongrongdong effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT haoliu effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT huanzhang effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT fengyangwu effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT haidongxiu effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT shiweichen effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT xinxiangyin effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens
AT xiaohuizhou effectsofbacillussubtiliszy1onproductionperformanceeggqualityserumparametersandintestinalhealthinlayinghens