Hypothyroidism Complicating Nephropathy in a Diabetes Patient

We describe a patient with type 2 diabetes mellitus and autoimmune hypothyroidism who presented with elevated serum creatinine possibly due to subclinical rhabdomyolysis induced by hypolipidemic drug therapy in the background of diabetic nephropathy. Both hypothyroidism and rhabdomyolysis were asymp...

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Main Authors: Jayaprakash Sahoo, Ilangovan Veerappan, Anila Abraham, Somasundaram Hariharan
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/237563
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author Jayaprakash Sahoo
Ilangovan Veerappan
Anila Abraham
Somasundaram Hariharan
author_facet Jayaprakash Sahoo
Ilangovan Veerappan
Anila Abraham
Somasundaram Hariharan
author_sort Jayaprakash Sahoo
collection DOAJ
description We describe a patient with type 2 diabetes mellitus and autoimmune hypothyroidism who presented with elevated serum creatinine possibly due to subclinical rhabdomyolysis induced by hypolipidemic drug therapy in the background of diabetic nephropathy. Both hypothyroidism and rhabdomyolysis were asymptomatic in this case as evidenced by lack of classical clinical features of hypothyroidism despite elevated serum TSH and absent pigment cast in renal biopsy. The combination of diabetes mellitus and hypothyroidism is common in the general population and should not be forgotten in patients with diabetes and kidney disease.
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series Case Reports in Endocrinology
spelling doaj-art-57f762e0b8174a4ca4d720de7609b3332025-02-03T01:20:28ZengWileyCase Reports in Endocrinology2090-65012090-651X2012-01-01201210.1155/2012/237563237563Hypothyroidism Complicating Nephropathy in a Diabetes PatientJayaprakash Sahoo0Ilangovan Veerappan1Anila Abraham2Somasundaram Hariharan3Department of Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry 605014, IndiaDepartment of Nephrology, Pondicherry Institute of Medical Sciences, Puducherry 605014, IndiaDepartment of Pathology, Madras Medical Mission, Chennai 600037, IndiaDepartment of Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry 605014, IndiaWe describe a patient with type 2 diabetes mellitus and autoimmune hypothyroidism who presented with elevated serum creatinine possibly due to subclinical rhabdomyolysis induced by hypolipidemic drug therapy in the background of diabetic nephropathy. Both hypothyroidism and rhabdomyolysis were asymptomatic in this case as evidenced by lack of classical clinical features of hypothyroidism despite elevated serum TSH and absent pigment cast in renal biopsy. The combination of diabetes mellitus and hypothyroidism is common in the general population and should not be forgotten in patients with diabetes and kidney disease.http://dx.doi.org/10.1155/2012/237563
spellingShingle Jayaprakash Sahoo
Ilangovan Veerappan
Anila Abraham
Somasundaram Hariharan
Hypothyroidism Complicating Nephropathy in a Diabetes Patient
Case Reports in Endocrinology
title Hypothyroidism Complicating Nephropathy in a Diabetes Patient
title_full Hypothyroidism Complicating Nephropathy in a Diabetes Patient
title_fullStr Hypothyroidism Complicating Nephropathy in a Diabetes Patient
title_full_unstemmed Hypothyroidism Complicating Nephropathy in a Diabetes Patient
title_short Hypothyroidism Complicating Nephropathy in a Diabetes Patient
title_sort hypothyroidism complicating nephropathy in a diabetes patient
url http://dx.doi.org/10.1155/2012/237563
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AT somasundaramhariharan hypothyroidismcomplicatingnephropathyinadiabetespatient