The expression pattern and role of circulating CXCR5+γδ T cells in children with newly diagnosed immune thrombocytopenia

IntroductionImmune thrombocytopenia (ITP) is the most common bleeding disorder in children. Tfh cells play a crucial role in the pathogenesis of ITP by promoting the production of anti-platelet autoantibodies. Recent studies have shown that CXCR5+γδ T cells not only possess “Tfh-like” cell functions...

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Main Authors: Jian-Yong Wang, Yi Xin, Xiao-Li Wang, Lin-Lin Li, Ai-Min Li, Xiao-Lu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1646877/full
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