Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis
Background. Oral direct-acting antivirals (DAAs) provide an exceptional opportunity to treat hepatitis C virus (HCV) infection. Goals. We compared the treatment outcomes between specialty and primary care physician (PCP) clinics for patients treated with DAAs. Methods. We performed a retrospective a...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2019/8434602 |
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| author | Taseen Ahmed Syed Muhammad Hassaan Bashir Samid Muhammad Farooqui Allshine Chen Sixia Chen Salman Nusrat Javid Fazili |
| author_facet | Taseen Ahmed Syed Muhammad Hassaan Bashir Samid Muhammad Farooqui Allshine Chen Sixia Chen Salman Nusrat Javid Fazili |
| author_sort | Taseen Ahmed Syed |
| collection | DOAJ |
| description | Background. Oral direct-acting antivirals (DAAs) provide an exceptional opportunity to treat hepatitis C virus (HCV) infection. Goals. We compared the treatment outcomes between specialty and primary care physician (PCP) clinics for patients treated with DAAs. Methods. We performed a retrospective analysis of patients treated for HCV in our PCP clinics and specialty; liver and gastroenterology clinics and gastroenterology clinics. We used the two-sided t-test and the chi-square test to compare the means of continuous and categorical variables, respectively. Results. Data from a total of 377 patients was analyzed (PCP clinic: n=185 and specialty clinic: n=192). There was no significant difference between age, race, and gender. Model for End-Stage Liver Disease (MELD) and Child-Turcotte-Pugh (CTP) scores were comparable at baseline. Greater than 90% of the patients achieved sustained virological response (SVR) with no difference between the groups. Conclusions. Uncomplicated patients can be treated for hepatitis C by their PCPs with DAAs with similar treatment outcomes to specialty clinics. There should be explicit guidelines on patient eligibility for treatment by PCPs vs. specialists. |
| format | Article |
| id | doaj-art-57e9bf4cff704b0b8de5f194f6f7003f |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-57e9bf4cff704b0b8de5f194f6f7003f2025-08-20T02:05:48ZengWileyGastroenterology Research and Practice1687-61211687-630X2019-01-01201910.1155/2019/84346028434602Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative AnalysisTaseen Ahmed Syed0Muhammad Hassaan Bashir1Samid Muhammad Farooqui2Allshine Chen3Sixia Chen4Salman Nusrat5Javid Fazili6Department of Internal Medicine, University of Oklahoma Health Sciences Center, 1100 N Lindsay Ave, Oklahoma City, OK 73104, USADepartment of Gastroenterology, SUNY Health Science Center, Brooklyn, New York, USADepartment of Internal Medicine, University of Oklahoma Health Sciences Center, 1100 N Lindsay Ave, Oklahoma City, OK 73104, USADepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, 801 NE 13th St., Oklahoma City, OK, USADepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, 801 NE 13th St., Oklahoma City, OK, USADepartment of Medicine, Neurogastroenterology and Motility Program, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Medicine, Section of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USABackground. Oral direct-acting antivirals (DAAs) provide an exceptional opportunity to treat hepatitis C virus (HCV) infection. Goals. We compared the treatment outcomes between specialty and primary care physician (PCP) clinics for patients treated with DAAs. Methods. We performed a retrospective analysis of patients treated for HCV in our PCP clinics and specialty; liver and gastroenterology clinics and gastroenterology clinics. We used the two-sided t-test and the chi-square test to compare the means of continuous and categorical variables, respectively. Results. Data from a total of 377 patients was analyzed (PCP clinic: n=185 and specialty clinic: n=192). There was no significant difference between age, race, and gender. Model for End-Stage Liver Disease (MELD) and Child-Turcotte-Pugh (CTP) scores were comparable at baseline. Greater than 90% of the patients achieved sustained virological response (SVR) with no difference between the groups. Conclusions. Uncomplicated patients can be treated for hepatitis C by their PCPs with DAAs with similar treatment outcomes to specialty clinics. There should be explicit guidelines on patient eligibility for treatment by PCPs vs. specialists.http://dx.doi.org/10.1155/2019/8434602 |
| spellingShingle | Taseen Ahmed Syed Muhammad Hassaan Bashir Samid Muhammad Farooqui Allshine Chen Sixia Chen Salman Nusrat Javid Fazili Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis Gastroenterology Research and Practice |
| title | Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis |
| title_full | Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis |
| title_fullStr | Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis |
| title_full_unstemmed | Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis |
| title_short | Treatment Outcomes of Hepatitis C-Infected Patients in Specialty Clinic vs. Primary Care Physician Clinic: A Comparative Analysis |
| title_sort | treatment outcomes of hepatitis c infected patients in specialty clinic vs primary care physician clinic a comparative analysis |
| url | http://dx.doi.org/10.1155/2019/8434602 |
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