Programmed cell death of platelets during their overactivation
Programmed cell death – it is a cell death by a strictly defined mechanism with possible impact on him and, due to this, the death control, including using of pharmacological agents. Currently known many different types of cell death, but only two basic types of cell death are adequately characteriz...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-01-01
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| Series: | Онкогематология |
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| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/124 |
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| author | E. O. Artemenko A. N. Sveshnikova M. A. Panteleev |
| author_facet | E. O. Artemenko A. N. Sveshnikova M. A. Panteleev |
| author_sort | E. O. Artemenko |
| collection | DOAJ |
| description | Programmed cell death – it is a cell death by a strictly defined mechanism with possible impact on him and, due to this, the death control, including using of pharmacological agents. Currently known many different types of cell death, but only two basic types of cell death are adequately characterized: apoptosis and programmed necrosis. Platelets are one of the key components of the blood clotting process. A group of platelets, exposing phosphatidylserine (PS), with the programmed cell death characteristics appears at their critical agonist-induced activation. This overactivation of platelets accompanied by subsequent cell death is not completely characterized cellular processes. We view the platelets overactivation in comparison with the main known types of cell death because the platelets group exposing PS is important for bloodcoagulation processes, accelerating by several orders the plasma coagulation, and important for the thrombus formation. |
| format | Article |
| id | doaj-art-57e8c433759c47bd97b327dcdbf4e30a |
| institution | Kabale University |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| publishDate | 2015-01-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj-art-57e8c433759c47bd97b327dcdbf4e30a2025-08-20T04:00:14ZrusABV-pressОнкогематология1818-83462413-40232015-01-0193636610.17650/1818-8346-2014-9-3-63-66139Programmed cell death of platelets during their overactivationE. O. Artemenko0A. N. Sveshnikova1M. A. Panteleev2Centre for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia, MoscowCentre for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia, MoscowCentre for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia, Moscow M.V. Lomonosov Moscow State UniversityProgrammed cell death – it is a cell death by a strictly defined mechanism with possible impact on him and, due to this, the death control, including using of pharmacological agents. Currently known many different types of cell death, but only two basic types of cell death are adequately characterized: apoptosis and programmed necrosis. Platelets are one of the key components of the blood clotting process. A group of platelets, exposing phosphatidylserine (PS), with the programmed cell death characteristics appears at their critical agonist-induced activation. This overactivation of platelets accompanied by subsequent cell death is not completely characterized cellular processes. We view the platelets overactivation in comparison with the main known types of cell death because the platelets group exposing PS is important for bloodcoagulation processes, accelerating by several orders the plasma coagulation, and important for the thrombus formation.https://oncohematology.abvpress.ru/ongm/article/view/124programmed cell deathcoagulationoveractivation of plateletsphosphatidylserine |
| spellingShingle | E. O. Artemenko A. N. Sveshnikova M. A. Panteleev Programmed cell death of platelets during their overactivation Онкогематология programmed cell death coagulation overactivation of platelets phosphatidylserine |
| title | Programmed cell death of platelets during their overactivation |
| title_full | Programmed cell death of platelets during their overactivation |
| title_fullStr | Programmed cell death of platelets during their overactivation |
| title_full_unstemmed | Programmed cell death of platelets during their overactivation |
| title_short | Programmed cell death of platelets during their overactivation |
| title_sort | programmed cell death of platelets during their overactivation |
| topic | programmed cell death coagulation overactivation of platelets phosphatidylserine |
| url | https://oncohematology.abvpress.ru/ongm/article/view/124 |
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