[18F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC)

[18F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC)

Purpose. Quantitative in vivo [18F]-(2S,4R)4-fluoroglutamine ([18F]4-FGln or more simply [18F]FGln) metabolic kinetic parameters are compared with activity levels of glutamine metabolism in different types of hepatocellular carcinoma (HCC). Methods. For this study, we used two transgenic mouse model...

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Bibliographic Details
Main Authors: Youngho Seo, Miranda C. Craig, Stephanie T. Murphy, Jinjin Feng, Xin Chen, Mariia Yuneva
Format: Article
Language:English
Published: SAGE Publishing 2022-01-01
Series:Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2022/5185951
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