3D‐Printed Titanium Trabecular Scaffolds with Sustained Release of Hypoxia‐Induced Exosomes for Dual‐Mimetic Bone Regeneration

3D‐Printed Titanium Trabecular Scaffolds with Sustained Release of Hypoxia‐Induced Exosomes for Dual‐Mimetic Bone Regeneration

Abstract Current Ti‐6Al‐4V bone implants lack trabecular structure and pro‑angiogenic cues, both essential for regeneration. Herein, a dual biomimetic strategy is devised that integrates a 3D‐printed biomimetic trabecular porous Ti‐6Al‐4V scaffold (BTPS) with exosome‐loaded PEGDA/GelMA hydrogel micr...

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Main Authors: Lincong Luo, Weihan Zheng, Jiaying Li, Tingting Chen, Wanting Xue, Tao Lin, Mingrui Liu, Zi Yan, Jiaxin Yang, Jiamin Li, Jiahao Pu, Yaobin Wu, Konghe Hu, Shiyu Li, Wenhua Huang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
3D‐printed
angiogenesis
biomimetic trabecular scaffold
bone regeneration, exosomes
Online Access:https://doi.org/10.1002/advs.202500599
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