Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural

As one of the most important platform chemicals, furfural (FAL) can be converted into high-value-added products such as furfuryl alcohol (FOL) through multiple pathways. Zirconium-based MOF-801 demonstrates exceptional catalytic potential for FAL conversion via catalytic transfer hydrogenation (CTH)...

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Main Authors: Yuxuan Liu, Qiuju Fu, Weijing Niu, Yingxin Zhang, Wenpeng Xie, Huimin Jiang, Liting Yan, Guangda Li, Xuebo Zhao
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/13/2697
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author Yuxuan Liu
Qiuju Fu
Weijing Niu
Yingxin Zhang
Wenpeng Xie
Huimin Jiang
Liting Yan
Guangda Li
Xuebo Zhao
author_facet Yuxuan Liu
Qiuju Fu
Weijing Niu
Yingxin Zhang
Wenpeng Xie
Huimin Jiang
Liting Yan
Guangda Li
Xuebo Zhao
author_sort Yuxuan Liu
collection DOAJ
description As one of the most important platform chemicals, furfural (FAL) can be converted into high-value-added products such as furfuryl alcohol (FOL) through multiple pathways. Zirconium-based MOF-801 demonstrates exceptional catalytic potential for FAL conversion via catalytic transfer hydrogenation (CTH), owing to its unique crystal defects generated during growth. In this study, a series of defective MOF-801 samples were efficiently synthesized using an air–liquid segmented microfluidic technique. The characterization results reveal that the air–liquid segmented flow method not only regulates the defect content of MOF-801 to expose more active sites but also adjusts the crystal size and pore structures by precisely controlling the reaction time. The enhanced defects in MOF-801 significantly improved its catalytic performance. A-MOF-801-64 exhibited the highest activity, achieving over 99% FAL conversion and 98% FOL selectivity under mild conditions (130 °C, 12 h) using isopropanol as the hydrogen donor; this performance surpassed that of other reported Zr-based catalysts. This study will facilitate the practical applications of defect-engineered MOF-801 in upgrading biomass-derived chemicals.
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institution Kabale University
issn 1420-3049
language English
publishDate 2025-06-01
publisher MDPI AG
record_format Article
series Molecules
spelling doaj-art-57db1b4d02b14c479f79b0d9fce195e52025-08-20T03:50:21ZengMDPI AGMolecules1420-30492025-06-013013269710.3390/molecules30132697Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of FurfuralYuxuan Liu0Qiuju Fu1Weijing Niu2Yingxin Zhang3Wenpeng Xie4Huimin Jiang5Liting Yan6Guangda Li7Xuebo Zhao8Advanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaCollege of Materials and Engineering, Qingdao University of Science and Technology, Qingdao 266042, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAdvanced Materials Institute, School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, ChinaAs one of the most important platform chemicals, furfural (FAL) can be converted into high-value-added products such as furfuryl alcohol (FOL) through multiple pathways. Zirconium-based MOF-801 demonstrates exceptional catalytic potential for FAL conversion via catalytic transfer hydrogenation (CTH), owing to its unique crystal defects generated during growth. In this study, a series of defective MOF-801 samples were efficiently synthesized using an air–liquid segmented microfluidic technique. The characterization results reveal that the air–liquid segmented flow method not only regulates the defect content of MOF-801 to expose more active sites but also adjusts the crystal size and pore structures by precisely controlling the reaction time. The enhanced defects in MOF-801 significantly improved its catalytic performance. A-MOF-801-64 exhibited the highest activity, achieving over 99% FAL conversion and 98% FOL selectivity under mild conditions (130 °C, 12 h) using isopropanol as the hydrogen donor; this performance surpassed that of other reported Zr-based catalysts. This study will facilitate the practical applications of defect-engineered MOF-801 in upgrading biomass-derived chemicals.https://www.mdpi.com/1420-3049/30/13/2697air–liquid segmented flowfurfuraldefective MOF-801catalytic transfer hydrogenationfurfuryl alcohol
spellingShingle Yuxuan Liu
Qiuju Fu
Weijing Niu
Yingxin Zhang
Wenpeng Xie
Huimin Jiang
Liting Yan
Guangda Li
Xuebo Zhao
Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural
Molecules
air–liquid segmented flow
furfural
defective MOF-801
catalytic transfer hydrogenation
furfuryl alcohol
title Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural
title_full Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural
title_fullStr Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural
title_full_unstemmed Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural
title_short Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural
title_sort synthesis of defective mof 801 via air liquid segmented flow for catalytic transfer hydrogenation of furfural
topic air–liquid segmented flow
furfural
defective MOF-801
catalytic transfer hydrogenation
furfuryl alcohol
url https://www.mdpi.com/1420-3049/30/13/2697
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